The molecular biology of plant acclimation to low temperature

MA Hughes, MA Dunn - Journal of Experimental Botany, 1996 - academic.oup.com
… That is, all of the genes are responsive to low temperature and not drought or ABA, but
the organ distribution of gene expression is different for each gene (Phillips and Hughes, …

[HTML][HTML] The 'complexities' of life and death: death receptor signalling platforms

LS Dickens, IR Powley, MA Hughes… - Experimental cell …, 2012 - Elsevier
Cell death is critical to the normal functioning of multi-cellular organisms, playing a central
role in development, immunity, inflammation, and cancer progression. Two cell death …

The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosis

RM Strieter, EC Keeley, MA Hughes… - Journal of leukocyte …, 2009 - academic.oup.com
Bone marrow-derived fibrocytes review as key cellular players in the promotion of the
pathogenesis of variety of fibroproliferative disorders, including pulmonary fibrosis. Pulmonary …

Context-sensitive half-time in multicompartment pharmacokinetic models for intravenous anesthetic drugs.

MA Hughes, PS Glass, JR Jacobs - Anesthesiology, 1992 - europepmc.org
Elimination half-life is the pharmacokinetic parameter used most commonly to describe
duration of pharmacologic action, including that expected of intravenous anesthetic drugs …

A fully integrated microfluidic genetic analysis system with sample-in–answer-out capability

…, MG Roper, SH Feldman, MA Hughes… - Proceedings of the …, 2006 - National Acad Sciences
We describe a microfluidic genetic analysis system that represents a previously undescribed
integrated microfluidic device capable of accepting whole blood as a crude biological …

The role of strength in rising from a chair in the functionally impaired elderly

MA Hughes, BS Myers, ML Schenkman - Journal of biomechanics, 1996 - Elsevier
… The foot, lower leg, and upper leg mass percentages were doubled based on the assumption
of left-right symmetry. Kinematic data were digitized and filtered using a fourth order, zero …

[PDF][PDF] A death effector domain chain DISC model reveals a crucial role for caspase-8 chain assembly in mediating apoptotic cell death

LS Dickens, RS Boyd, R Jukes-Jones, MA Hughes… - Molecular cell, 2012 - cell.com
… Using quantitative mass spectrometry, we have delineated the stoichiometry of the native
TRAIL DISC. While current models suggest that core DISC components are present at a ratio of …

Chair rise strategies in the elderly

MA Hughes, DK Weiner, ML Schenkman, RM Long… - Clinical …, 1994 - Elsevier
The elderly often have difficulty with rising from a chair. The purpose of this study was to
characterize their rising strategies. A group of 22 elderly adults with a range of functional …

The relative importance of strength and balance in chair rise by functionally impaired older individuals

M Schenkman, MA Hughes, G Samsa… - Journal of the …, 1996 - Wiley Online Library
OBJECTIVE: The ability to stand independently and safely from the seated position is
essential for independent function. This investigation determined the relative contributions of …

[PDF][PDF] Co-operative and hierarchical binding of c-FLIP and caspase-8: a unified model defines how c-FLIP isoforms differentially control cell fate

MA Hughes, IR Powley, R Jukes-Jones, S Horn… - Molecular cell, 2016 - cell.com
… Moreover, using quantitative mass spectrometry and confocal imaging, we show that
high levels of c-FLIPS (or c-FLIPL) inhibit DISC activation by blocking formation of DED-mediated …