A recombinant adenovirus serotype 5 (rAd5) vector-based vaccine for HIV-1 has recently
failed in a phase 2b efficacy study in humans 1 , 2 . Consistent with these results, preclinical …

Recombinant adenovirus serotype 5 (rAd5) vaccine vectors for human immunodeficiency
virus type 1 (HIV-1) and other pathogens have been shown to elicit antigen-specific cellular …

Human and chimpanzee adenovirus vectors are being developed to circumvent preexisting
antibodies against common adenovirus vectors such as Ad5. However, baseline immunity to …

Clinical trials in malignant glioma have demonstrated excellent safety of recombinant
adenovirus type 5 (Ad5) but lack of convincing efficacy. The overall low expression levels of the …

Proteases of the plasminogen activator (PA) and matrix metalloproteinase (MMP) system
play an important role in smooth muscle cell (SMC) migration and neointima formation after …

This review article offers an engagement with Nicholas Wolterstorff’s recent publication, Acting
liturgically: Philosophical reflections on religious practice. It begins by contextualising the …

Following the centenary year of the publication of the first edition of Karl Barth’s Der
Römerbrief, this article attempts to look at what a contemporary South African audience could …

This essay reflects theologically on rhythm by turning to the North African church father
Augustine, specifically his work De musica. It begins by briefly referring to recent theological work …

Rationale Transforming growth factor-beta (TGFβ) is tightly regulated at multiple levels, with
regulation at the receptor level now recognized as a key determinant of the cellular …

This article investigates the important South African anti-apartheid protest play, Woza Albert!,
written and performed in 1981 by Percy Mtwa and Mbogeni Ngema, which retells the story …