Huntington disease is devastating to patients and their families—with autosomal dominant
inheritance, onset typically in the prime of adult life, progressive course, and a combination of …

Background The topical role of uric acid and its relation to cardiovascular disease, renal
disease, and hypertension is rapidly evolving. Its important role both historically and currently in …

… Hayden … Hayden … Attie, AD, JP Kastelein, and MR Hayden. Pivotal role of ABCA1 in
reverse cholesterol transport influencing HDL levels and susceptibility to atherosclerosis. …

Genes have a major role in the control of high-density lipoprotein (HDL) cholesterol (HDL-C)
levels. Here we have identified two Tangier disease (TD) families, confirmed 9q31 linkage …

… Moreover, apart from GALAH and the Gaia/ESO survey, these other studies are limited to
MR spectroscopy (R < 10,000; Figure 1), and so they are unable to provide reliably the kind of …

Huntingtin is a 350-kilodalton protein of unknown function that is mutated in Huntington's
disease (HD), a neurodegenerative disorder. The mutant protein is presumed to acquire a toxic …

Huntington's disease (HD) is associated with the expansion of a CAG trinucleotide repeat in
a novel gene. We have assessed 360 HD individuals from 259 unrelated families and found …

Juvenile hemochromatosis is an early-onset autosomal recessive disorder of iron overload
resulting in cardiomyopathy, diabetes and hypogonadism that presents in the teens and early …

Huntington's disease (HD) is caused by an expansion of exonic CAG triplet repeats in the
gene encoding huntingtin protein (Htt), but the mechanisms by which this mutant protein …

Huntington's disease (HD) is a neurodegenerative disorder caused by an unstable CAG
repeat. For patients at risk, participating in predictive testing and learning of having CAG …