Endometriosis is a common condition associated with debilitating pelvic pain and infertility.
A genome-wide association study meta-analysis, including 60,674 cases and 701,926 …

Designing PCR primers for amplifying regions of eukaryotic genomes is a complicated task
because the genomes contain a large number of repeat sequences and other regions …

Rare copy-number variants (rCNVs) include deletions and duplications that occur infrequently
in the global human population and can confer substantial risk for disease. In this study, …

There is considerable inter-individual variability in susceptibility to weight gain despite an
equally obesogenic environment in large parts of the world. Whereas many studies have …

Miscarriage is a common, complex trait affecting ~15% of clinically confirmed pregnancies.
Here we present the results of large-scale genetic association analyses with 69,054 cases …

Purpose Biomedical databases combining electronic medical records and phenotypic and
genomic data constitute a powerful resource for the personalization of treatment. To leverage …

The impact of copy-number variations (CNVs) on complex human traits remains
understudied. We called CNVs in 331,522 UK Biobank participants and performed genome-wide …

Pernicious anemia is a rare condition characterized by vitamin B12 deficiency anemia due
to lack of intrinsic factor, often caused by autoimmune gastritis. Patients with pernicious …

Hypersensitivity reactions to drugs are often unpredictable and can be life threatening,
underscoring a need for understanding their underlying mechanisms and risk factors. The extent …

Background Fast, accurate and high-throughput identification of bacterial isolates is in great
demand. The present work was conducted to investigate the possibility of identifying isolates …