Organoids are self‐organizing 3D structures grown from stem cells that recapitulate essential
aspects of organ structure and function. Here, we describe a method to establish long‐term…

Excessive release of neutrophil extracellular traps (NETs) is associated with disease severity
and contributes to tissue injury, followed by severe organ damage. Pharmacological or …

In spite of their important role in host defense, neutrophils can also cause severe morbidity
and mortality. Neutrophils have an extensive armory necessary to eradicate pathogens, but …

Fibrosis is a major cause of mortality worldwide, characterized by myofibroblast activation
and excessive extracellular matrix deposition. Systemic sclerosis is a prototypic fibrotic …

A wide variety of microbial and inflammatory factors induce DNA release from neutrophils
as neutrophil extracellular traps (NETs). Consensus on the kinetics and mechanism of NET …

Objectives Increased release of neutrophil extracellular traps (NETs) is implicated in the
activation of plasmacytoid dendritic cells, vascular disease and thrombosis in SLE and APS. …

Objective Gout is the most common inflammatory arthritis worldwide, and patients experience
a heavy burden of cardiovascular and metabolic diseases. The inflammation is caused by …

In response to microbial invasion, neutrophils release neutrophil extracellular traps (NETs)
to trap and kill extracellular microbes. Alternatively, NET formation can result in tissue …

Signal inhibitory receptor on leukocytes‐1 (SIRL‐1) is an inhibitory receptor with a hitherto
unknown ligand, and is expressed on human monocytes and neutrophils. SIRL‐1 inhibits …

LDGs are a subset of proinflammatory neutrophils which numbers are increased in patients
with SLE as well as other rheumatic diseases including antineutrophil cytoplasmic …