A bone-specific adipogenesis pathway in fat-free mice defines key origins and adaptations of bone marrow adipocytes with age and disease

X Zhang, H Robles, KL Magee, MR Lorenz, Z Wang… - Elife, 2021 - elifesciences.org
Bone marrow adipocytes accumulate with age and in diverse disease states. However, their
origins and adaptations in these conditions remain unclear, impairing our understanding of …

A neuroskeletal atlas: spatial mapping and contextualization of axon subtypes innervating the long bones of C3H and B6 mice

MR Lorenz, JM Brazill, AT Beeve, I Shen… - Journal of Bone and …, 2020 - academic.oup.com
Nerves in bone play well‐established roles in pain and vasoregulation and have been
associated with progression of skeletal disorders, including osteoporosis, fracture, arthritis, and …

[HTML][HTML] Shared autonomic pathways connect bone marrow and peripheral adipose tissues across the central neuraxis

NKY Wee, MR Lorenz, Y Bekirov, MF Jacquin… - Frontiers in …, 2019 - frontiersin.org
Bone marrow adipose tissue (BMAT) is increased in both obesity and anorexia. This is
unique relative to white adipose tissue (WAT), which is generally more attuned to metabolic …

Reambulation following hindlimb unloading attenuates disuse-induced changes in murine fracture healing

…, RC DeNapoli, LB Abraham, JA Denisco, MR Lorenz… - Bone, 2023 - Elsevier
Patients with bone and muscle loss from prolonged disuse have higher risk of falls and
subsequent fragility fractures. In addition, fracture patients with continued disuse and/or delayed …

[HTML][HTML] Bone marrow adipose tissue does not express UCP1 during development or adrenergic-induced remodeling

CS Craft, H Robles, MR Lorenz, ED Hilker, KL Magee… - Scientific reports, 2019 - nature.com
Adipocytes within the skeleton are collectively termed bone marrow adipose tissue (BMAT).
BMAT contributes to peripheral and local metabolism, however, its capacity for cell-…

Immunostaining of skeletal tissues

C Idleburg, MR Lorenz, EN DeLassus… - Osteoporosis and …, 2021 - Springer
Immunostaining is the process of identifying proteins in tissue sections by incubating the
sample with antibodies specific to the protein of interest, then visualizing the bound antibody …

Corrigendum: Shared Autonomic Pathways Connect Bone Marrow and Peripheral Adipose Tissues Across the Central Neuraxis

NKY Wee, MR Lorenz, Y Bekirov, MF Jacquin… - Frontiers in …, 2020 - frontiersin.org
Lorenz 1 Yusuf Bekirov Yusuf Bekirov 1 Mark F. Jacquin Mark F. Jacquin 3 Erica L. …
Citation: Wee NKY, Lorenz MR, Bekirov Y, Jacquin MF and Scheller EL (2020) Corrigendum …

A novel skeletal-specific adipogenesis pathway defines key origins and adaptations of bone marrow adipocytes with age and disease

H Robles, X Zhang, KL Magee, MR Lorenz, Z Wang… - BioRxiv, 2021 - biorxiv.org
Bone marrow adipocytes (BMAs) accumulate with age and in diverse disease states. However,
their age- and disease-specific origins and adaptations remain unclear, impairing our …

A neuroskeletal atlas of the mouse limb

MR Lorenz, JM Brazill, A Beeve, I Shen, EL Scheller - bioRxiv, 2020 - biorxiv.org
Nerves in bone play well-established roles in pain and vasoregulation and have been
associated with progression of skeletal disorders including osteoporosis, fracture, arthritis and …

[BOOK][B] Osteoporosis and osteoarthritis

AJ Van Wijnen, MS Ganshina, van Wijnen - 2021 - Springer
Musculoskeletal regenerative medicine and orthopedic research examine molecular mechanisms,
cellular pathways, and animal models for skeletal degeneration. The translational end…