User profiles for Madhuvanthi Kannan

Madhuvanthi Kannan

Assistant professor, University of Minnesota Neuroscience
Verified email at umn.edu
Cited by 397

Fast, in vivo voltage imaging using a red fluorescent indicator

M Kannan, G Vasan, C Huang, S Haziza, JZ Li… - Nature …, 2018 - nature.com
Genetically encoded voltage indicators (GEVIs) are emerging optical tools for acquiring
brain-wide cell-type-specific functional data at unparalleled temporal resolution. To broaden the …

Dual-polarity voltage imaging of the concurrent dynamics of multiple neuron types

M Kannan, G Vasan, S Haziza, C Huang… - Science, 2022 - science.org
Genetically encoded fluorescent voltage indicators are ideally suited to reveal the
millisecond-scale interactions among and between targeted cell populations. However, current …

[HTML][HTML] Optimizing strategies for developing genetically encoded voltage indicators

M Kannan, G Vasan, VA Pieribone - Frontiers in Cellular …, 2019 - frontiersin.org
Genetically encoded optical indicators of neuronal activity enable unambiguous recordings
of input-output activity patterns from identified cells in intact circuits. Among them, genetically …

Visual deprivation during the critical period enhances layer 2/3 GABAergic inhibition in mouse V1

M Kannan, GG Gross, DB Arnold… - Journal of …, 2016 - Soc Neuroscience
The role of GABAergic signaling in establishing a critical period for experience in visual
cortex is well understood. However, the effects of early experience on GABAergic synapses …

[HTML][HTML] Regulation of neuronal survival and morphology by the E3 ubiquitin ligase RNF157

…, D Zanini, A Holubowska, M Kannan… - Cell Death & …, 2015 - nature.com
Neuronal health is essential for the long-term integrity of the brain. In this study, we characterized
the novel E3 ubiquitin ligase ring finger protein 157 (RNF157), which displays a brain-…

The E3 ligase Cdh1-anaphase promoting complex operates upstream of the E3 ligase Smurf1 in the control of axon growth

M Kannan, SJ Lee, N Schwedhelm-Domeyer… - …, 2012 - journals.biologists.com
Axon growth is an essential event during brain development and is extremely limited due to
extrinsic and intrinsic inhibition in the adult brain. The E3 ubiquitin ligase Cdh1-anaphase …

Dopamine signals integrate innate and learnt valences to regulate memory dynamics

…, SJ Woo, L Roitman, J Li, V Pieribone, M Kannan… - 2022 - researchsquare.com
To survive in dynamic environments, animals make behavioral decisions based on innate
and learnt information about the valences of sensory cues. In the brains of multiple species, …

[HTML][HTML] p250GAP is a novel player in the Cdh1-APC/Smurf1 pathway of axon growth regulation

M Kannan, SJ Lee, N Schwedhelm-Domeyer… - PLoS …, 2012 - journals.plos.org
Axon growth is an essential process during brain development. The E3 ubiquitin ligase
Cdh1-APC has emerged as a critical regulator of intrinsic axon growth control. Here, we …

Mevastatin accelerates loss of synaptic proteins and neurite degeneration in aging cortical neurons in a heme-independent manner

M Kannan, JR Steinert, ID Forsythe, AG Smith… - Neurobiology of …, 2010 - Elsevier
The therapeutic use of statins in reducing cholesterol requires careful assessment of potential
neuroprotective and/or neurotoxic mechanisms. Chronic treatment with mevastatin (MV) …

Dual polarity voltage imaging reveals subthreshold dynamics and concurrent spiking patterns of multiple neuron-types

M Kannan, G Vasan, S Haziza, C Huang… - Biorxiv, 2021 - biorxiv.org
Genetically encoded fluorescent voltage indicators are ideally suited to reveal the
millisecond-scale interactions among and between distinct, targeted cell populations. However, …