User profiles for Madhuvanthi Kannan
Madhuvanthi KannanAssistant professor, University of Minnesota Neuroscience Verified email at umn.edu Cited by 397 |
Fast, in vivo voltage imaging using a red fluorescent indicator
Genetically encoded voltage indicators (GEVIs) are emerging optical tools for acquiring
brain-wide cell-type-specific functional data at unparalleled temporal resolution. To broaden the …
brain-wide cell-type-specific functional data at unparalleled temporal resolution. To broaden the …
Dual-polarity voltage imaging of the concurrent dynamics of multiple neuron types
Genetically encoded fluorescent voltage indicators are ideally suited to reveal the
millisecond-scale interactions among and between targeted cell populations. However, current …
millisecond-scale interactions among and between targeted cell populations. However, current …
[HTML][HTML] Optimizing strategies for developing genetically encoded voltage indicators
Genetically encoded optical indicators of neuronal activity enable unambiguous recordings
of input-output activity patterns from identified cells in intact circuits. Among them, genetically …
of input-output activity patterns from identified cells in intact circuits. Among them, genetically …
Visual deprivation during the critical period enhances layer 2/3 GABAergic inhibition in mouse V1
The role of GABAergic signaling in establishing a critical period for experience in visual
cortex is well understood. However, the effects of early experience on GABAergic synapses …
cortex is well understood. However, the effects of early experience on GABAergic synapses …
[HTML][HTML] Regulation of neuronal survival and morphology by the E3 ubiquitin ligase RNF157
…, D Zanini, A Holubowska, M Kannan… - Cell Death & …, 2015 - nature.com
Neuronal health is essential for the long-term integrity of the brain. In this study, we characterized
the novel E3 ubiquitin ligase ring finger protein 157 (RNF157), which displays a brain-…
the novel E3 ubiquitin ligase ring finger protein 157 (RNF157), which displays a brain-…
The E3 ligase Cdh1-anaphase promoting complex operates upstream of the E3 ligase Smurf1 in the control of axon growth
M Kannan, SJ Lee, N Schwedhelm-Domeyer… - …, 2012 - journals.biologists.com
Axon growth is an essential event during brain development and is extremely limited due to
extrinsic and intrinsic inhibition in the adult brain. The E3 ubiquitin ligase Cdh1-anaphase …
extrinsic and intrinsic inhibition in the adult brain. The E3 ubiquitin ligase Cdh1-anaphase …
Dopamine signals integrate innate and learnt valences to regulate memory dynamics
To survive in dynamic environments, animals make behavioral decisions based on innate
and learnt information about the valences of sensory cues. In the brains of multiple species, …
and learnt information about the valences of sensory cues. In the brains of multiple species, …
[HTML][HTML] p250GAP is a novel player in the Cdh1-APC/Smurf1 pathway of axon growth regulation
M Kannan, SJ Lee, N Schwedhelm-Domeyer… - PLoS …, 2012 - journals.plos.org
Axon growth is an essential process during brain development. The E3 ubiquitin ligase
Cdh1-APC has emerged as a critical regulator of intrinsic axon growth control. Here, we …
Cdh1-APC has emerged as a critical regulator of intrinsic axon growth control. Here, we …
Mevastatin accelerates loss of synaptic proteins and neurite degeneration in aging cortical neurons in a heme-independent manner
The therapeutic use of statins in reducing cholesterol requires careful assessment of potential
neuroprotective and/or neurotoxic mechanisms. Chronic treatment with mevastatin (MV) …
neuroprotective and/or neurotoxic mechanisms. Chronic treatment with mevastatin (MV) …
Dual polarity voltage imaging reveals subthreshold dynamics and concurrent spiking patterns of multiple neuron-types
Genetically encoded fluorescent voltage indicators are ideally suited to reveal the
millisecond-scale interactions among and between distinct, targeted cell populations. However, …
millisecond-scale interactions among and between distinct, targeted cell populations. However, …