User profiles for Maga Rowicka

Maga Rowicka

Associate Professor, University of Texas Medical Branch at Galveston
Verified email at utmb.edu
Cited by 3223

Logic of the yeast metabolic cycle: temporal compartmentalization of cellular processes

BP Tu, A Kudlicki, M Rowicka, SL McKnight - Science, 2005 - science.org
Budding yeast grown under continuous, nutrient-limited conditions exhibit robust, highly
periodic cycles in the form of respiratory bursts. Microarray studies reveal that over half of the …

Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing

…, M Skrzypczak, K Ginalski, P Pasero, M Rowicka… - Nature …, 2013 - nature.com
We present a genome-wide approach to map DNA double-strand breaks (DSBs) at nucleotide
resolution by a method we termed BLESS (direct in situ breaks labeling, enrichment on …

[PDF][PDF] Comprehensive mapping of histone modifications at DNA double-strand breaks deciphers repair pathway chromatin signatures

…, B Fongang, N Dojer, JS Iacovoni, M Rowicka… - Molecular cell, 2018 - cell.com
Double-strand breaks (DSBs) are extremely detrimental DNA lesions that can lead to cancer-driving
mutations and translocations. Non-homologous end joining (NHEJ) and …

Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes

…, M Skrzypczak, K Ginalski, M Rowicka… - Nature structural & …, 2017 - nature.com
The ability of DNA double-strand breaks (DSBs) to cluster in mammalian cells has been a
subject of intense debate in recent years. Here we used a high-throughput chromosome …

[HTML][HTML] Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites

…, A Sarrazin, C Mettling, M Rowicka… - Nature …, 2020 - nature.com
R-loops have both positive and negative impacts on chromosome functions. To identify toxic
R-loops in the human genome, here, we map RNA:DNA hybrids, replication stress markers …

Valosin-containing protein (p97) is a regulator of endoplasmic reticulum stress and of the degradation of N-end rule and ubiquitin-fusion degradation pathway …

C Wójcik, M Rowicka, A Kudlicki, D Nowis… - Molecular biology of …, 2006 - Am Soc Cell Biol
Valosin-containing protein (VCP; p97; cdc48 in yeast) is a hexameric ATPase of the AAA family
(ATPases with multiple cellular activities) involved in multiple cellular functions, including …

[HTML][HTML] Strategies for achieving high sequencing accuracy for low diversity samples and avoiding sample bleeding using illumina platform

A Mitra, M Skrzypczak, K Ginalski, M Rowicka - PloS one, 2015 - journals.plos.org
Sequencing microRNA, reduced representation sequencing, Hi-C technology and any
method requiring the use of in-house barcodes result in sequencing libraries with low initial …

[HTML][HTML] Comprehensive Structural and Substrate Specificity Classification of the Saccharomyces cerevisiae Methyltransferome

…, L Knizewski, L Rychlewski, A Kudlicki, M Rowicka… - PloS one, 2011 - journals.plos.org
Methylation is one of the most common chemical modifications of biologically active
molecules and it occurs in all life forms. Its functional role is very diverse and involves many …

High-resolution timing of cell cycle-regulated gene expression

M Rowicka, A Kudlicki, BP Tu… - Proceedings of the …, 2007 - National Acad Sciences
The eukaryotic cell division cycle depends on an intricate sequence of transcriptional events.
Using an algorithm based on maximum-entropy deconvolution, and expression data from a …

[HTML][HTML] qDSB-Seq is a general method for genome-wide quantification of DNA double-strand breaks using sequencing

…, R Yousefi, P Pasero, K Ginalski, M Rowicka - Nature …, 2019 - nature.com
DNA double-strand breaks (DSBs) are among the most lethal types of DNA damage and
frequently cause genome instability. Sequencing-based methods for mapping DSBs have been …