User profiles for Magdalena E. Sobieszczyk

Magdalena Sobieszczyk

Columbia University Irving Medical Center
Verified email at cumc.columbia.edu
Cited by 15323

[HTML][HTML] Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2

…, C Yoon, KKW To, H Chen, MT Yin, ME Sobieszczyk… - Nature, 2022 - nature.com
The B.1.1.529/Omicron variant of SARS-CoV-2 was only recently detected in southern Africa,
but its subsequent spread has been extensive, both regionally and globally 1 . It is …

[HTML][HTML] Phase 3 safety and efficacy of AZD1222 (ChAdOx1 nCoV-19) Covid-19 vaccine

AR Falsey, ME Sobieszczyk, I Hirsch… - … England Journal of …, 2021 - Mass Medical Soc
Background The safety and efficacy of the AZD1222 (ChAdOx1 nCoV-19) vaccine in a large,
diverse population at increased risk for severe acute respiratory syndrome coronavirus 2 (…

[HTML][HTML] Antibody evasion properties of SARS-CoV-2 Omicron sublineages

…, H Chu, KKH Chik, TTT Yuen, MT Yin, ME Sobieszczyk… - Nature, 2022 - nature.com
The identification of the Omicron (B. 1.1. 529.1 or BA. 1) variant of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) in Botswana in November 2021 1 immediately …

[HTML][HTML] Antibody evasion by SARS-CoV-2 Omicron subvariants BA. 2.12. 1, BA. 4 and BA. 5

…, Z Chen, K Meyers, MT Yin, ME Sobieszczyk… - Nature, 2022 - nature.com
SARS-CoV-2 Omicron subvariants BA.2.12.1 and BA.4/5 have surged notably to become
dominant in the United States and South Africa, respectively 1 , 2 . These new subvariants …

[HTML][HTML] Observational study of hydroxychloroquine in hospitalized patients with Covid-19

…, C Kubin, RG Barr, ME Sobieszczyk… - … England Journal of …, 2020 - Mass Medical Soc
Background Hydroxychloroquine has been widely administered to patients with Covid-19
without robust evidence supporting its use. Methods We examined the association between …

Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: retrospective case series

…, NW Schluger, S Sengupta, ME Sobieszczyk… - bmj, 2020 - bmj.com
Objective To characterize patients with coronavirus disease 2019 (covid-19) in a large New
York City medical center and describe their clinical course across the emergency department…

The challenge of HIV-1 subtype diversity

BS Taylor, ME Sobieszczyk… - … England Journal of …, 2008 - Mass Medical Soc
HIV-1 has evolved multiple mechanisms to elude immune control. The view of virus as
classifiable into distinct subtypes needs to reflect the reality of the constant emergence of new …

[HTML][HTML] Efficacy trial of a DNA/rAd5 HIV-1 preventive vaccine

SM Hammer, ME Sobieszczyk, H Janes… - … England Journal of …, 2013 - Mass Medical Soc
Background A safe and effective vaccine for the prevention of human immunodeficiency
virus type 1 (HIV-1) infection is a global priority. We tested the efficacy of a DNA prime–…

[HTML][HTML] Two randomized trials of neutralizing antibodies to prevent HIV-1 acquisition

…, I Frank, J Hinojosa, ME Sobieszczyk… - … England Journal of …, 2021 - Mass Medical Soc
Background Whether a broadly neutralizing antibody (bnAb) can be used to prevent human
immunodeficiency virus type 1 (HIV-1) acquisition is unclear. Methods We enrolled at-risk …

Acute liver injury in COVID‐19: prevalence and association with clinical outcomes in a large US cohort

…, LH Barraza, ED LaSota, ME Sobieszczyk… - …, 2020 - Wiley Online Library
Background and Aims Coronavirus disease 2019 (COVID‐19) has been associated with acute
liver injury (ALI) manifested by increased liver enzymes in reports worldwide. Prevalence …