Directed evolution of enzymes toward improved catalytic performance has become a powerful
tool in protein engineering. To be effective, a directed evolution campaign requires the …

Proteins are the workhorses of the cell and, over billions of years, they have evolved an
amazing plethora of extremely diverse and versatile structures with equally diverse functions. …

Introduction Comparative genomics has become an important strategy in life science
research. While many genes, and the proteins they code for, can be well characterized by …

Hydrolysis of organic sulfate esters proceeds by two distinct mechanisms, water attacking at
either sulfur (S–O bond cleavage) or carbon (C–O bond cleavage). In primary and …

Evolutionary pathways by which proteins have evolved in Nature over billions of years have
resulted in an impressive diversity of structures that carry out many functions with unrivalled …

… The authors thank Dr Magdalena Heberlein for her preparatory work in the generation of a
maximum-likelihood phylogenetic tree and the reconstruction of ancestral protein sequences. …

The objective of this study was to investigate the variability of flexural strength for flame-sprayed
ceramic components and to determine which two-parametric distribution function was …

… Twelve years later Magdalena decided at age 50 to emigrate together with the family of
her son-in-law to the United States. It was Dorothea Gadient, born in Mastrils on December 2, …