Multiple sites on SARS‐CoV‐2 spike protein are susceptible to proteolysis by cathepsins B, K, L, S, and V

K Bollavaram, TH Leeman, MW Lee, A Kulkarni… - Protein …, 2021 - Wiley Online Library
SARS‐CoV‐2 is the coronavirus responsible for the COVID‐19 pandemic. Proteases are
central to the infection process of SARS‐CoV‐2. Cleavage of the spike protein on the virus's …

[PDF][PDF] Project “Chopsticks”

…, LIU Guanzhong, T YAMANAKA, WOO Maggie - geijutsu.tsukuba.ac.jp
While the Pan Pacific Region gradually emerges as an economic and political powerhouse
in the 21stCentury, people in the area tend to be apathetic toward their own traditions due to …

Peginterferon alfa-2a and ribavirin in patients with chronic hepatitis C who have failed prior treatment

…, AS Lok, TR Morgan, HL Bonkovsky, WM Lee… - Gastroenterology, 2004 - Elsevier
Background & Aims: The most effective therapy currently available for treatment of chronic
hepatitis C virus (HCV) is the combination of peginterferon and ribavirin. This study evaluated …

Soft, curved electrode systems capable of integration on the auricle as a persistent brain–computer interface

JJS Norton, DS Lee, JW Lee, W Lee… - Proceedings of the …, 2015 - National Acad Sciences
Recent advances in electrodes for noninvasive recording of electroencephalograms
expand opportunities collecting such data for diagnosis of neurological disorders and brain–…

Broken barriers: a new take on sepsis pathogenesis

…, BE Steinberg, AS Slutsky, WL Lee - Science translational …, 2011 - science.org
Despite intense research into the pathogenesis of sepsis, the current therapy for this
devastating syndrome is primarily supportive and mortality remains high. The paucity of specific …

Humanization of T cell–mediated immunity in mice

…, A Dhanik, KA Meagher, A Karr, J Roos, W Lee… - Science …, 2021 - science.org
Despite the enormous promise of T cell therapies, the isolation and study of human T cell
receptors (TCRs) of dedicated specificity remains a major challenge. To overcome this …

Serum alpha-fetoprotein levels in patients with advanced hepatitis C: results from the HALT-C Trial

…, GT Everson, KL Lindsay, ASF Lok, WM Lee… - Journal of …, 2005 - Elsevier
BACKGROUND/AIMS: Alpha-fetoprotein (AFP) has been useful in the diagnosis of hepatocellular
carcinoma (HCC) but lacks specificity. We assessed serum AFP among patients with …

Symmetry-breaking orbital anisotropy observed for detwinned Ba(Fe1-xCox)2As2 above the spin density wave transition

…, RG Moore, M Hashimoto, WS Lee… - Proceedings of the …, 2011 - National Acad Sciences
Nematicity, defined as broken rotational symmetry, has recently been observed in
competing phases proximate to the superconducting phase in the cuprate high-temperature …

Genome-wide mapping of human loci for essential hypertension

…, R Dobson, J Knight, S Newhouse, J Hooper, W Lee… - The Lancet, 2003 - thelancet.com
Background Blood pressure may contribute to 50% of the global cardiovascular disease
epidemic. By understanding the genes predisposing to common disorders such as human …

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

…, C Langenberg, EB Larson, NR Lee, WJ Lee… - Nature …, 2019 - nature.com
Body-fat distribution is a risk factor for adverse cardiovascular health consequences. We
analyzed the association of body-fat distribution, assessed by waist-to-hip ratio adjusted for …