DNA origami signaling units transduce chemical and mechanical signals in synthetic cells
Transmembrane proteins transmit chemical signals as well as mechanical cues. The latter
is often achieved by coupling to the cytoskeleton. The incorporation of fully engineerable …
is often achieved by coupling to the cytoskeleton. The incorporation of fully engineerable …
A DNA segregation module for synthetic cells
The bottom‐up construction of an artificial cell requires the realization of synthetic cell
division. Significant progress has been made toward reliable compartment division, yet …
division. Significant progress has been made toward reliable compartment division, yet …
[PDF][PDF] Interspecies transcriptomics identify genes that underlie disproportionate foot growth in jerboas
Despite the great diversity of vertebrate limb proportion and our deep understanding of the
genetic mechanisms that drive skeletal elongation, little is known about how individual bones …
genetic mechanisms that drive skeletal elongation, little is known about how individual bones …
Amphiphiles formed from synthetic DNA-nanomotifs mimic the stepwise dispersal of transcriptional clusters in the cell nucleus
X Tschurikow, A Gadzekpo, MP Tran, R Chatterjee… - Nano Letters, 2023 - ACS Publications
Stem cells exhibit prominent clusters controlling the transcription of genes into RNA. These
clusters form by a phase-separation mechanism, and their size and shape are controlled via …
clusters form by a phase-separation mechanism, and their size and shape are controlled via …
Length-tuneable biocompatible block copolymer nanorods with a poly (2-methyl-2-oxazine)-corona via heat-induced crystallisation-driven self-assembly
Polymer-based nanoparticle (NP) morphology and surface chemistry are important factors
to consider when it comes to their stability, biocompatibility, and biodistribution. Poly(2-…
to consider when it comes to their stability, biocompatibility, and biodistribution. Poly(2-…
Changing while staying the same: Preservation of structural continuity during limb evolution by developmental integration
More than 150 years since Charles Darwin published “On the Origin of Species”, gradual
evolution by natural selection is still not fully reconciled with the apparent sudden appearance …
evolution by natural selection is still not fully reconciled with the apparent sudden appearance …
Telithromycin: a novel agent for the treatment of community-acquired upper respiratory infections
MP Tran - Baylor University Medical Center Proceedings, 2004 - Taylor & Francis
The ketolides are a new subclass of macrolides, and telithromycin is the first of these agents
to be approved. Modifications to the basic macrolide structure result in enhanced activity …
to be approved. Modifications to the basic macrolide structure result in enhanced activity …
Evolutionary loss of foot muscle during development with characteristics of atrophy and no evidence of cell death
10.7554/eLife.50645.001 Many species that run or leap across sparsely vegetated habitats,
including horses and deer, evolved the severe reduction or complete loss of foot muscles as …
including horses and deer, evolved the severe reduction or complete loss of foot muscles as …
Gene expression differences associated with intrinsic hindfoot muscle loss in the jerboa, Jaculus jaculus
MP Tran, D Ochoa Reyes, AJ Weitzel, A Saxena… - bioRxiv, 2024 - biorxiv.org
Vertebrate animals that run or jump across sparsely vegetated habitats, such as horses and
jerboas, have reduced the number of distal limb bones, and many have lost most or all distal …
jerboas, have reduced the number of distal limb bones, and many have lost most or all distal …
Targeting mitochondrial translation by inhibiting DDX3: a novel radiosensitization strategy for cancer treatment
… age at diagnosis (P=0.042), higher mitotic activity index (MAI; P=0.002), ductal histological
type (P=0.003), higher grade (P=0.002), negative estrogen (P=0.005) and progesterone (…
type (P=0.003), higher grade (P=0.002), negative estrogen (P=0.005) and progesterone (…