Photochemical OFF/ON cytotoxicity switching by using a photochromic surfactant with visible light irradiation

M Shinohara, Y Ashikaga, W Xu, S Kim… - ACS …, 2022 - ACS Publications
Photochemical switching of cytotoxicity by using spiropyran compounds with pyridinium and
alkyl groups was investigated. The spiropyran compound, SP6, with a hexyl group as the …

[HTML][HTML] Analysis of the Effects of Food Additives on Porphyromonas gingivalis

M Shinohara, M Maetani, C Kitada, Y Nishigami… - Pathogens, 2022 - mdpi.com
This study aims to investigate six food additives (octanoic acid, decanoic acid, acesulfame K,
aspartame, saccharin, and sucralose) used in foods for the elderly or people with …

Identification and Analysis of Monoclonal Antibodies with Neutralizing Activity against Diverse SARS-CoV-2 Variants

…, Y Kurahashi, K Furukawa, M Shinohara… - Journal of …, 2023 - Am Soc Microbiol
We identified neutralizing monoclonal antibodies against severe acute respiratory syndrome-coronavirus
2 (SARS-CoV-2) variants (including Omicron variants BA.5 and BA.2.75) from …

Postprandial plasma glucagon kinetics in type 2 diabetes mellitus: comparison of immunoassay and mass spectrometry

T Katahira, A Kanazawa, M Shinohara… - Journal of the …, 2019 - academic.oup.com
Context Accurate glucagon level measurements are necessary for investigation of mechanisms
for postprandial hyperglycemia in type 2 diabetes. Objective To evaluate the accuracy of …

Effect of plasma exchange in thyroid storm with consideration of its distribution into the extravascular space

M Shinohara, T Uchida, T Funayama… - Journal of the …, 2020 - academic.oup.com
Plasma exchange (PE), which directly removes some plasma thyroid hormones, is a treatment
option for thyroid storm. However, the effect of PE has not been accurately assessed yet. …

Photo-control of cellular uptake by the selective adsorption of spiropyran derivatives on albumin

M Shinohara, W Xu, S Kim, T Fukaminato… - Chemistry …, 2022 - academic.oup.com
A photochromic spiropyran derivative (SP6) as a drug tag was prepared. SP6 was selectively
taken up into cells by photo-controlling the adsorption on albumin, which has attracted …

Effect of real‐life insulin pump with predictive low‐glucose management use for 3 months: Analysis of the patients treated in a Japanese center

…, N Waseda, M Koshibu, M Shinohara… - Journal of Diabetes …, 2020 - Wiley Online Library
Aims/Introduction In Japan, an insulin pump with predictive low‐glucose management (PLGM)
was launched in 2018. It automatically suspends insulin delivery when the sensor detects …

Novel monoclonal antibodies showing broad neutralizing activity for SARS-CoV-2 variants including Omicrons BA. 5 and BA. 2.75

…, K Aoki, Y Kurahashi, K Furukawa, M Shinohara… - bioRxiv, 2022 - biorxiv.org
We identified novel neutralizing monoclonal antibodies against SARS-CoV-2 variants (including
Omicron) from individuals received two doses of mRNA vaccination after they had been …

[HTML][HTML] KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress

JR Moonen, J Chappell, M Shi, T Shinohara… - Nature …, 2022 - nature.com
Physiologic laminar shear stress (LSS) induces an endothelial gene expression profile that
is vasculo-protective. In this report, we delineate how LSS mediates changes in the …

International photographic classification and grading system for myopic maculopathy

…, CCW Klaver, M Moriyama, K Shinohara… - American journal of …, 2015 - Elsevier
Purpose To develop a classification and grading system for myopic maculopathy. Design
Development and evaluation of a classification system for myopic maculopathy based on …