User profiles for Maia L. Corpuz

Maia Corpuz

University of Southern California
Verified email at usc.edu
Cited by 207

[HTML][HTML] Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases

…, C Yu, R van Damme, WH Lee, ML Corpuz… - Nature …, 2021 - nature.com
Direct determination of RNA structures and interactions in living cells is critical for understanding
their functions in normal physiology and disease states. Here, we present PARIS2, a …

PDE8 Is Expressed in Human Airway Smooth Muscle and Selectively Regulates cAMP Signaling by β2-Adrenergic Receptors and Adenylyl Cyclase 6

…, F Li, AG Kazarian, ML Corpuz… - American journal of …, 2018 - atsjournals.org
Two cAMP signaling compartments centered on adenylyl cyclase (AC) exist in human airway
smooth muscle (HASM) cells, one containing β 2 -adrenergic receptor AC6 and another …

[HTML][HTML] Glucocorticoids rapidly activate cAMP production via Gαs to initiate non‐genomic signaling that contributes to one‐third of their canonical genomic effects

FJ Nuñez, TB Johnstone, ML Corpuz… - The FASEB …, 2020 - ncbi.nlm.nih.gov
Glucocorticoids are widely used for the suppression of inflammation, but evidence is growing
that they can have rapid, non‐genomic actions that have been unappreciated. Diverse cell …

Budesonide enhances agonist-induced bronchodilation in human small airways by increasing cAMP production in airway smooth muscle

…, TB Johnstone, ML Corpuz… - … of Physiology-Lung …, 2020 - journals.physiology.org
The nongenomic mechanisms by which glucocorticoids modulate β 2 agonist-induced-bronchodilation
remain elusive. Our studies aimed to elucidate mechanisms mediating the …

The mitogen-activated protein kinase pathway facilitates resistance to the src inhibitor dasatinib in thyroid cancer

…, SM Riffert, KE Wuensch, BE Kessler, ML Corpuz… - Molecular cancer …, 2016 - AACR
Advanced stages of papillary and anaplastic thyroid cancer represent a highly aggressive
subset, in which there are currently few effective therapies. We and others have recently …

Transforming Growth Factor-β1 Decreases β2-Agonist–induced Relaxation in Human Airway Smooth Muscle

…, A Schwab, AL Fuentes, ML Corpuz… - American journal of …, 2019 - atsjournals.org
Helper T effector cytokines implicated in asthma modulate the contractility of human airway
smooth muscle (HASM) cells. We have reported recently that a profibrotic cytokine, …

Optimized photochemistry and enzymology enable efficient analysis of RNA structures and interactions in cells and virus infections

…, J Bai, C Yu, R van Damme, WH Lee, ML Corpuz… - bioRxiv, 2020 - biorxiv.org
Direct determination of RNA structures and interactions in living cells is critical for
understanding their functions. Current crosslinking and proximity-ligation approaches are …

Characterization of Proanthocyanidins as a Biomarker for Wood Quality in the Native Timber-Wood Tree Acacia koa.

ML Corpuz - 2017 - scholarspace.manoa.hawaii.edu
Acacia koa (koa) is an economically valuable timber wood tree playing an important role for
Hawaiian culture and ecology. Wood color of koa can range from blond to dark red while its …

Glucocorticoids rapidly stimulate cAMP production in a Gαs‐dependent manner

FJ Nuñez, ML Corpuz, DM Fogel, KT Lyon… - The FASEB …, 2020 - Wiley Online Library
Glucocorticoids have wide therapeutic applications in inflammation and immune disorders
and have traditionally been used to treat diseases such as asthma and COPD. They exert …

[HTML][HTML] Dysregulation of Immature Sertoli Cell Functions by Exposure to Acetaminophen and Genistein in Rodent Cell Models

M Corpuz-Hilsabeck, N Mohajer, M Culty - Cells, 2023 - mdpi.com
Sertoli cells are essential for germ cell development and function. Their disruption by endocrine
disrupting chemicals (EDCs) or drugs could jeopardize spermatogenesis, contributing to …