User profiles for Makoto Arai
Makoto AraiChiba University Verified email at umin.ac.jp Cited by 7904 |
Influence of hepatitis B virus genotypes on the progression of chronic type B liver disease
To investigate the hepatitis B virus (HBV) genotype-related differences in the progression of
liver disease, 585 patients with chronic HBV infection including 258 with histologically …
liver disease, 585 patients with chronic HBV infection including 258 with histologically …
Structure of pathological TDP-43 filaments from ALS with FTLD
D Arseni, M Hasegawa, AG Murzin, F Kametani, M Arai… - Nature, 2022 - nature.com
The abnormal aggregation of TAR DNA-binding protein 43 kDa (TDP-43) in neurons and glia
is the defining pathological hallmark of the neurodegenerative disease amyotrophic lateral …
is the defining pathological hallmark of the neurodegenerative disease amyotrophic lateral …
Brain cannabinoid CB2 receptor in schizophrenia
…, ES Onaivi, H Kunugi, T Sasaki, M Itokawa, M Arai… - Biological …, 2010 - Elsevier
BACKGROUND: Neural endocannabinoid function appears to be involved in schizophrenia.
Two endocannabinoid receptors, CB1 and CB2, are found in the brain and elsewhere in the …
Two endocannabinoid receptors, CB1 and CB2, are found in the brain and elsewhere in the …
[PDF][PDF] Comparative analyses of copy-number variation in autism spectrum disorder and schizophrenia reveal etiological overlap and biological insights
…, J Egawa, A Nunokawa, M Itokawa, M Arai… - Cell reports, 2018 - cell.com
Compelling evidence in Caucasian populations suggests a role for copy-number variations (CNVs)
in autism spectrum disorder (ASD) and schizophrenia (SCZ). We analyzed 1,108 …
in autism spectrum disorder (ASD) and schizophrenia (SCZ). We analyzed 1,108 …
Subthalamic deep brain stimulation can improve gastric emptying in Parkinson's disease
It is established that deep brain stimulation of the subthalamic nucleus improves motor
function in advanced Parkinson’s disease, but its effects on autonomic function remain to be …
function in advanced Parkinson’s disease, but its effects on autonomic function remain to be …
Enhanced carbonyl stress in a subpopulation of schizophrenia
M Arai, H Yuzawa, I Nohara, T Ohnishi… - Archives of general …, 2010 - jamanetwork.com
Context Various factors are involved in the pathogenesis of schizophrenia. Accumulation of
advanced glycation end products, including pentosidine, results from carbonyl stress, a state …
advanced glycation end products, including pentosidine, results from carbonyl stress, a state …
Involvement of SMARCA2/BRM in the SWI/SNF chromatin-remodeling complex in schizophrenia
…, H Ishiguro, S Yazaki, Y Horiuchi, M Arai… - Human molecular …, 2009 - academic.oup.com
Chromatin remodeling may play a role in the neurobiology of schizophrenia and the process,
therefore, may be considered as a therapeutic target. The SMARCA2 gene encodes BRM …
therefore, may be considered as a therapeutic target. The SMARCA2 gene encodes BRM …
Randomized phase II trial comparing site-specific treatment based on gene expression profiling with carboplatin and paclitaxel for patients with cancer of unknown …
H Hayashi, T Kurata, Y Takiguchi, M Arai… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE Although gene expression profiling is a promising diagnostic technique to
determine the tissue of origin for patients with cancer of unknown primary site (CUP), no clinical …
determine the tissue of origin for patients with cancer of unknown primary site (CUP), no clinical …
Inhibition of TGF-β1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis
Y Akagi, Y Isaka, M Arai, T Kaneko, M Takenaka… - Kidney international, 1996 - Elsevier
glomerulonephritis Page 1 Kidney International, Vol. 50 (1996), pp. 148–155 Inhibition of
TGF-81 expression by antisense oligonucleotides suppressed extracellular matrix …
TGF-81 expression by antisense oligonucleotides suppressed extracellular matrix …
[HTML][HTML] Evidence-based clinical practice guidelines for functional dyspepsia 2021
H Miwa, A Nagahara, A Asakawa, M Arai… - Journal of …, 2022 - Springer
Background Functional dyspepsia (FD) is a disorder that presents with chronic dyspepsia,
which is not only very common but also highly affects quality of life of the patients. In Japan, …
which is not only very common but also highly affects quality of life of the patients. In Japan, …