Mouse retinal cell atlas: molecular identification of over sixty amacrine cell types
Amacrine cells (ACs) are a diverse class of interneurons that modulate input from photoreceptors
to retinal ganglion cells (RGCs), rendering each RGC type selectively sensitive to …
to retinal ganglion cells (RGCs), rendering each RGC type selectively sensitive to …
Combinatorial effects of alpha-and gamma-protocadherins on neuronal survival and dendritic self-avoidance
…, AD Sing, KS Joseph, MA Laboulaye… - Journal of …, 2018 - Soc Neuroscience
The clustered protocadherins (Pcdhs) comprise 58 cadherin-related proteins encoded by
three tandemly arrayed gene clusters, Pcdh-α, Pcdh-β, and Pcdh-γ (Pcdha, Pcdhb, and Pcdhg, …
three tandemly arrayed gene clusters, Pcdh-α, Pcdh-β, and Pcdh-γ (Pcdha, Pcdhb, and Pcdhg, …
[PDF][PDF] Cadherin combinations recruit dendrites of distinct retinal neurons to a shared interneuronal scaffold
Distinct neuronal types connect in complex ways to generate functional neural circuits. The
molecular diversity required to specify this connectivity could be supplied by multigene …
molecular diversity required to specify this connectivity could be supplied by multigene …
Tbr1 instructs laminar patterning of retinal ganglion cell dendrites
Visual information is delivered to the brain by >40 types of retinal ganglion cells (RGCs).
Diversity in this representation arises within the inner plexiform layer (IPL), where dendrites of …
Diversity in this representation arises within the inner plexiform layer (IPL), where dendrites of …
[HTML][HTML] Mapping transgene insertion sites reveals complex interactions between mouse transgenes and neighboring endogenous genes
Transgenic mouse lines are routinely employed to label and manipulate distinct cell types.
The transgene generally comprises cell-type specific regulatory elements linked to a cDNA …
The transgene generally comprises cell-type specific regulatory elements linked to a cDNA …
Mechanisms of oxidative stress in interstitial cystitis/bladder pain syndrome
A Mohammad, MA Laboulaye, C Shenhar… - Nature Reviews …, 2024 - nature.com
Interstitial cystitis/bladder pain syndrome (IC/BPS) is characterized by bladder and/or pelvic
pain, increased urinary urgency and frequency and nocturia. The pathophysiology of IC/BPS …
pain, increased urinary urgency and frequency and nocturia. The pathophysiology of IC/BPS …
Molecular identification of sixty-three amacrine cell types completes a mouse retinal cell atlas
Amacrine cells (ACs) are a diverse class of interneurons that modulate input from photoreceptors
to retinal ganglion cells (RGCs), rendering each RGC type selectively sensitive to …
to retinal ganglion cells (RGCs), rendering each RGC type selectively sensitive to …
[PDF][PDF] Mapping Transgene Insertion Sites Reveals Complex Interactions Between Mouse
MA Laboulaye, X Duan, M Qiao - 2018 - core.ac.uk
Transgenic mouse lines are routinely employed to label and manipulate distinct cell types.
The transgene generally comprises cell-type specific regulatory elements linked to a cDNA …
The transgene generally comprises cell-type specific regulatory elements linked to a cDNA …
Molecular classification of cell types in the human trabecular meshwork and surrounding structures using single-cell RNAseq
Purpose: Trabecular meshwork (TM), a complex tissue responsible for IOP homeostasis, is
composed of cells whose molecular identities are incompletely characterized. We sought to …
composed of cells whose molecular identities are incompletely characterized. We sought to …
Shh/Hoxa4 Pathway Regulates Spinal Disc Regeneration via Resident Skeletal Stem Cells
M Hoover, H Chen, M Laboulaye, J Sokol, A Alam… - papers.ssrn.com
The intervertebral disc, also known as the spinal disc, deteriorates faster than other connective
tissues, leading to spinal disc degeneration. Addressing this requires effective treatments …
tissues, leading to spinal disc degeneration. Addressing this requires effective treatments …