User profiles for Malte Rühlemann

Malte Christoph Rühlemann

IKMB, Kiel University
Verified email at ikmb.uni-kiel.de
Cited by 8090

[HTML][HTML] Reporting guidelines for human microbiome research: the STORMS checklist

…, E Pasolli, J Raes, MR Redinbo, M Rühlemann… - Nature medicine, 2021 - nature.com
The particularly interdisciplinary nature of human microbiome research makes the organization
and reporting of results spanning epidemiology, biology, bioinformatics, translational …

Large-scale association analyses identify host factors influencing human gut microbiome composition

…, MJ Bonder, TH Hansen, F Frost, MC Rühlemann… - Nature …, 2021 - nature.com
To study the effect of host genetics on gut microbiome composition, the MiBioGen consortium
curated and analyzed genome-wide genotypes and 16S fecal microbiome data from …

Genome-wide association analysis identifies variation in vitamin D receptor and other host factors influencing the gut microbiota

…, JR Hov, F Degenhardt, FA Heinsen, MC Rühlemann… - Nature …, 2016 - nature.com
Human gut microbiota is an important determinant for health and disease, and recent
studies emphasize the numerous factors shaping its diversity. Here we performed a genome-wide …

[HTML][HTML] Functions of the microbiota for the physiology of animal metaorganisms

…, L Best, D Prasse, J Bathia, MC Rühlemann… - Journal of innate …, 2019 - karger.com
Animals are usually regarded as independent entities within their respective environments.
However, within an organism, eukaryotes and prokaryotes interact dynamically to form the so-…

[HTML][HTML] Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum

…, TH Hansen, T Nielsen, KH Allin, MC Rühlemann… - Microbiome, 2018 - Springer
Background Imbalances of gut microbiota composition are linked to a range of metabolic
perturbations. In the present study, we examined the gut microbiota of women with gestational …

[PDF][PDF] Obese individuals with and without type 2 diabetes show different gut microbial functional capacity and composition

LB Thingholm, MC Rühlemann, M Koch, B Fuqua… - Cell host & …, 2019 - cell.com
Obesity and type 2 diabetes (T2D) are metabolic disorders that are linked to microbiome
alterations. However, their co-occurrence poses challenges in disentangling microbial features …

Heart failure is associated with depletion of core intestinal microbiota

…, T Winkler, FA Heinsen, MC Rühlemann… - ESC heart …, 2017 - Wiley Online Library
Aims In spite of current medical treatment approaches, mortality of chronic heart failure (HF)
remains high and novel treatment modalities are thus urgently needed. A recent theory …

Genome-wide associations of human gut microbiome variation and implications for causal inference analyses

…, R Bacigalupe, J Wang, MC Rühlemann… - Nature …, 2020 - nature.com
Recent population-based 1 , 2 , 3 – 4 and clinical studies 5 have identified a range of factors
associated with human gut microbiome variation. Murine quantitative trait loci 6 , human …

Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis

A Worthmann, C John, MC Rühlemann, M Baguhl… - Nature medicine, 2017 - nature.com
Adaptive thermogenesis is an energy-demanding process that is mediated by cold-activated
beige and brown adipocytes, and it entails increased uptake of carbohydrates, as well as …

[HTML][HTML] Comparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms

P Rausch, M Rühlemann, BM Hermes, S Doms… - Microbiome, 2019 - Springer
Background The interplay between hosts and their associated microbiome is now recognized
as a fundamental basis of the ecology, evolution, and development of both players. These …