Neuron-glia interactions play a critical role in the regulation of synapse formation and circuit
assembly. Here we demonstrate that canonical Sonic hedgehog (Shh) pathway signaling in …

The cerebral cortex contains billions of neurons, and their disorganization or misspecification
leads to neurodevelopmental disorders. Understanding how the plethora of projection …

The septum is a ventral forebrain structure known to regulate innate behaviors. During
embryonic development, septal neurons are produced in multiple proliferative areas from neural …

Over the last several decades the field has made tremendous progress in understanding
the proliferative behavior of cortical progenitors and the lineage relationships of their clonal …

Astrocyte specification during development is influenced by both intrinsic and extrinsic factors,
but the precise contribution of each remains poorly understood. Here we show that septal …

The mammalian cortex is populated by neurons derived from neural progenitors located
throughout the embryonic telencephalon. Excitatory neurons are derived from the dorsal …

The gene EHMT1 that encodes the Euchromatic Histone Methyltransferase-1, also known
as GLP (G9a-like protein), has been associated with a number of neurodevelopmental and …

Regulators of chromatin dynamics and transcription are increasingly implicated in the
aetiology of neurodevelopmental disorders. Haploinsufficiency of EHMT1, encoding a histone …

Neuron-glia relationships play a critical role in the regulation of synapse formation and neuronal
specification. The cellular and molecular mechanisms by which neurons and astrocytes …

The polymorphic merozoite surface protein (MSP-1) of Plasmodium falciparum is a major
asexual blood-stage malaria vaccine candidate. Immunological mechanisms responsible for …