Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation during Drosophila development

L Zhou, MYT Lim, P Kaur, A Saj, D Bortolamiol-Becet… - Elife, 2018 - elifesciences.org
10.7554/eLife.38389.001 Mature microRNAs (miRNAs) are processed from primary
transcripts (pri-miRNAs), and their expression is controlled at transcriptional and post-transcriptional …

[PDF][PDF] The Drosophila Dicer-1 partner loquacious enhances miRNA processing from hairpins with unstable structures at the dicing site

MYT Lim, AWT Ng, Y Chou, TP Lim, A Simcox… - Cell reports, 2016 - cell.com
In Drosophila, Dicer-1 binds Loquacious-PB (Loqs-PB) as its major co-factor. Previous
analyses indicated that loqs mutants only partially impede miRNA processing, but the activity of …

[HTML][HTML] A novel eukaryotic RdRP-dependent small RNA pathway represses antiviral immunity by controlling an ERK pathway component in the black-legged tick

C Feng, K Torimaru, MYT Lim, LL Chak, M Shiimori… - PloS one, 2023 - journals.plos.org
Small regulatory RNAs (sRNAs) are involved in antiviral defense and gene regulation.
Although roles of RNA-dependent RNA Polymerases (RdRPs) in sRNA biology are extensively …

Different modes of regulation govern miRNA expression levels in Drosophila melanogaster

MYT Lim - 2019 - dr.ntu.edu.sg
MiRNAs are a class of small non-coding RNAs that play important roles in post-transcriptional
regulation of complementary target mRNAs. Loquacious (Loqs) is a dsRNA-binding …

RNA-dependent RNA polymerases in the black-legged tick produce Argonaute-dependent small RNAs and regulate genes

C Feng, K Torimaru, MYT Lim, LL Chak, K Tsuji… - bioRxiv, 2021 - biorxiv.org
Small regulatory RNAs (sRNAs) are involved in anti-viral defense and gene regulation. Although
RNA-dependent RNA Polymerases (RdRPs) are known to produce sRNA in nematodes…

Switches in Dicer activity during oogenesis and early development

MYT Lim, K Okamura - Oocytes: Maternal Information and Functions, 2017 - Springer
Dicer is a versatile protein regulating diverse biological processes via the production of multiple
classes of small regulatory RNAs, including microRNAs (miRNAs) and small interfering …

Temperament traits in captive non-human primates and the potential consequences on reproductive success.

MYT Lim - 2012 - dr.ntu.edu.sg
Temperament traits in non-human primates have received increasing attention due to its
potential contribution to fitness. Temperament differences may determine which species are …

Drive: Detecting malicious roadside units in the internet of vehicles with low latency data integrity

NV Abhishek, MN Aman, TJ Lim… - IEEE Internet of Things …, 2021 - ieeexplore.ieee.org
The Internet of Vehicles (IoV) may enhance road safety, improve traffic flow, etc. However,
Internet-connected intelligent vehicles (IVs) are vulnerable to cyber-attacks. One of the …

Gastric cancer (biomarkers) knowledgebase (GCBKB): a curated and fully integrated knowledgebase of putative biomarkers related to gastric cancer

…, P Vijayakumar, L Liew, J Lim, YP Lim… - Biomarker …, 2006 - journals.sagepub.com
The Gastric Cancer (Biomarkers) Knowledgebase (GCBKB) ( http://biomarkers.bii.a-star.edu.sg/background/gastricCancerBiomarkersKb.php
) is a curated and fully integrated …

[HTML][HTML] The next wave: key adaptations to operational workflows of National Screening Centre (Singapore) and the emergency department during the COVID-19 …

…, M Loh, AHJ Lim, J Kwan, HJ Teo, DKP Teng… - International Journal Of …, 2021 - Springer
In the initial phases of the COVID-19 pandemic, Singapore received international recognition
for her outbreak response and was regarded as the “gold standard” by international …