A previous placebo-controlled trial has shown that biodegradable 1,3-bis (2-chloroethyl)-1-nitrosourea
(BCNU) wafers (Gliadel wafers) prolong survival in patients with recurrent …

Accurate pathological diagnosis is crucial for optimal management of patients with cancer.
For the approximately 100 known tumour types of the central nervous system, standardization …

In response to major changes in diagnostic algorithms and the publication of mature results
from various large clinical trials, the European Association of Neuro-Oncology (EANO) …

Binding of programmed death ligand-1 (PD-L1) to programmed cell death protein-1 (PD1)
leads to cancer immune evasion via inhibition of T cell function. One of the defining …

Angiogenesis is a possible target in the treatment of human gliomas. To evaluate the role of
3 growth factors, vascular endothelial growth factor (VEGF), hepatocyte growth factor/scatter …

INVADING GLIOMA CELLS seem to follow distinct anatomic structures within the central
nervous system. Tumor cell dissemination may occur along structures, such as the basement …

The European Association for Neuro-Oncology guideline provides recommendations for the
clinical care of adult patients with astrocytic and oligodendroglial gliomas, including …

WHO grading of human brain tumors extends beyond a strictly histological grading system
by providing a basis predictive for the clinical behavior of the respective neoplasm. For …

PURPOSE: NovoTTF-100A is a portable device delivering low-intensity, intermediate
frequency electric fields via non-invasive, transducer arrays. Tumour Treatment Fields (TTF), a …

Gliomas are the most common type of primary brain tumour and are often fast growing with a
poor prognosis for the patient. Their complex cellular composition, diffuse invasiveness and …