User profiles for Manil Kanade

Manil Kanade

IISER Pune
Verified email at students.iiserpune.ac.in
Cited by 107

On the emergence of P-Loop NTPase and Rossmann enzymes from a Beta-Alpha-Beta ancestral fragment

LM Longo, J Jabłońska, P Vyas, M Kanade, R Kolodny… - Elife, 2020 - elifesciences.org
This article is dedicated to the memory of Michael G. Rossmann. Dating back to the last universal
common ancestor, P-loop NTPases and Rossmanns comprise the most ubiquitous and …

[HTML][HTML] Allosteric regulation of a prokaryotic small Ras-like GTPase contributes to cell polarity oscillations in bacterial motility

J Baranwal, S Lhospice, M Kanade, S Chakraborty… - PLoS …, 2019 - journals.plos.org
Mutual gliding motility A (MglA), a small Ras-like GTPase; Mutual gliding motility B (MglB), its
GTPase activating protein (GAP); and Required for Motility Response Regulator (RomR), a …

A distinct motif in a prokaryotic small Ras-Like GTPase highlights unifying features of walker B motifs in P-Loop NTPases

M Kanade, S Chakraborty, SS Shelke… - Journal of molecular …, 2020 - Elsevier
A hallmark of the catalytically essential Walker B motif of P-loop NTPases is the presence of
an acidic residue (aspartate/glutamate) for efficient Mg 2+ coordination. Although the Walker …

[HTML][HTML] Mechanism of GTPase activation of a prokaryotic small Ras-like GTPase MglA by an asymmetrically interacting MglB dimer

S Chakraborty, M Kanade, P Gayathri - Journal of Biological Chemistry, 2024 - ASBMB
Cell polarity oscillations in Myxococcus xanthus motility are driven by a prokaryotic small
Ras-like GTPase, mutual gliding protein A (MglA), which switches from one cell pole to the …

Dual specificity of a prokaryotic GTPase‐activating protein (GAP) to two small Ras‐like GTPases in Myxococcus xanthus

M Kanade, NB Singh, S Lagad, J Baranwal… - The FEBS …, 2021 - Wiley Online Library
Two small Ras‐like GTPases, MglA and SofG, work in synchrony to drive cell polarity and
motility in the soil bacterium, Myxococcus xanthus. While MglA regulates two types of motility in …

Biochemical characterization of two prokaryotic small Ras-like GTPases and their common effector

M Kanade - 2019 - dr.iiserpune.ac.in
Dynamic cell polarity is crucial for many cellular activities. In Myxococcus xanthus MglA, a
small Ras-like GTPase, and MglB, its GTPase activating protein (GAP), along with RomR (…

A Distinct Motif in a Prokaryotic Small Ras-Like GTPase Highlights Unifying Features of Walker B Motifs in P-Loop NTPases

…, S CHAKRABORTY, G PANANGHAT, M KANADE - 2020 - dr.iiserpune.ac.in
A hallmark of the catalytically essential Walker B motif of P-loop NTPases is the presence of
an acidic residue (aspartate/glutamate) for efficient Mg2+ coordination. Although the Walker …

Allosteric regulation of a prokaryotic small Ras-like GTPase contributes to cell polarity oscillations in bacterial motility

…, J Herrou, J BARANWAL, S Lhospice, M KANADE… - 2019 - dr.iiserpune.ac.in
Mutual gliding motility A (MglA), a small Ras-like GTPase; Mutual gliding motility B (MglB), its
GTPase activating protein (GAP); and Required for Motility Response Regulator (RomR), a …

Real-time control of CMU direct-drive arm II using customized inverse dynamics

T Kanade, PK Khosia, N Tanaka - The 23rd IEEE Conference …, 1984 - ieeexplore.ieee.org
… for the real-lime control of high.speed manil;ulators. In the next section, we deslgn our
customized NE algorithm for the DD Arm II and r*duce further the actual computatlonal …

Structural and Biochemical studies of SofG, a GTPase involved in bacterial cell motility

S LAGAD - 2017 - dr.iiserpune.ac.in
Cell motility is one of the important functions performed by the bacteria in order to survive.
Myxococcus xanthus, a rod shaped bacteria exhibits two different types of motility namely …