Global deployment of vaccines that can provide protection across several age groups is still
urgently needed to end the COVID-19 pandemic, especially in low- and middle-income …

Viral clearance requires effector T-cell egress from the draining lymph node (dLN). The
mechanisms that regulate the complex process of effector T-cell egress from the dLN after …

The SARS-CoV-2 Omicron variant evades vaccine-induced immunity. While a booster dose
of ancestral mRNA vaccines effectively elicits neutralizing antibodies against variants, its …

Infection is the most common cause of mortality early in life, yet the broad potential of
immunization is not fully realized in this vulnerable population. Most vaccines are administered …

Adjuvanted nanocarrier-based vaccines hold substantial potential for applications in novel
early-life immunization strategies. Here, via mouse and human age-specific in vitro modeling, …

Abstract Development of SARS-CoV-2 vaccines that protect vulnerable populations is a
public health priority. Here, we took a systematic and iterative approach by testing several …

The large GTPase dynamin is well known for its actions on budded cellular membranes to
generate vesicles, most often, clathrin-coated endocytic vesicles. The scope of cellular …

Global deployment of vaccines that can provide protection across several age groups is still
urgently needed to end the COVID-19 pandemic especially for low- and middle-income …

Mounting a protective immune response is critically dependent on the orchestrated movement
of cells within lymphoid tissues. The structure of secondary lymphoid organs regulates …

Actin networks in migrating cells exist as several interdependent structures: sheet-like
networks of branched actin filaments in lamellipodia; arrays of bundled actin filaments co-…