Biocatalysis, one of the oldest technologies, is becoming a favorable alternative to chemical
processes and a vital part of green technology. It is an important revenue generating …

The developing paradigms about YKL-40, a member of the “mammalian chitinase-like
proteins”, from across the globe, project it as a vital parameter for the detection of disease onset …

The ability to manipulate specific neuronal populations of the spinal cord following spinal cord
injury (SCI) could prove highly beneficial for rehabilitation in patients through maintaining …

The need to develop efficient therapies for neurodegenerative diseases is urgent, especially
given the increasing percentages of the population living longer, with increasing chances of …

Cell migration is the hallmark of cancer regulating anchorage independent growth and
invasiveness of tumor cells. Hyaluronan (HA), an ECM polysaccharide is shown to regulate this …

Understanding percepts, engrams and actions requires methods for selectively modulating
synaptic communication between specific subsets of interconnected cells. Here, we develop …

In genetic and pharmacological models of neurodevelopmental disorders, and human data,
neural activity is altered within the developing neocortical network. This commonality begs …

Irrespective of the many strategies focused on dealing with spinal cord injury (SCI), there is
still no way to restore motor function efficiently or an adequate regenerative therapy. One …

Significance Bioluminescent optogenetics (BL-OG) offers a unique and powerful approach
to manipulate neural activity both opto- and chemogenetically using a single actuator …

Combined deficiencies of poly (ADP) ribosyl polymerase 1 (PARP1) and ataxia telangiectasia
mutated (ATM) result in synthetic lethality and, in the mouse, early embryonic death. Here, …