User profiles for Manuel Ares
 | Manuel Ares, Jr.University of California, Santa Cruz Verified email at ucsc.edu Cited by 21950 |
Context-dependent control of alternative splicing by RNA-binding proteins
XD Fu, M Ares Jr - Nature Reviews Genetics, 2014 - nature.com
Sequence-specific RNA-binding proteins (RBPs) bind to pre-mRNA to control alternative
splicing, but it is not yet possible to read the 'splicing code' that dictates splicing regulation on …
splicing, but it is not yet possible to read the 'splicing code' that dictates splicing regulation on …
Knowledge-based analysis of microarray gene expression data by using support vector machines
We introduce a method of functionally classifying genes by using gene expression data from
DNA microarray hybridization experiments. The method is based on the theory of support …
DNA microarray hybridization experiments. The method is based on the theory of support …
Purification of RNA using TRIzol (TRI reagent)
TRIzol solubilization and extraction is a relatively recently developed general method for
deproteinizing RNA. This method is particularly advantageous in situations where cells or …
deproteinizing RNA. This method is particularly advantageous in situations where cells or …
An RNA gene expressed during cortical development evolved rapidly in humans
The developmental and evolutionary mechanisms behind the emergence of human-specific
brain features remain largely unknown. However, the recent ability to compare our genome …
brain features remain largely unknown. However, the recent ability to compare our genome …
A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons
Many metazoan gene transcripts exhibit neuron-specific splicing patterns, but the developmental
control of these splicing events is poorly understood. We show that the splicing of a …
control of these splicing events is poorly understood. We show that the splicing of a …
Ultraconserved elements are associated with homeostatic control of splicing regulators by alternative splicing and nonsense-mediated decay
Many alternative splicing events create RNAs with premature stop codons, suggesting that
alternative splicing coupled with nonsense-mediated decay (AS-NMD) may regulate gene …
alternative splicing coupled with nonsense-mediated decay (AS-NMD) may regulate gene …
Genomewide analysis of mRNA processing in yeast using splicing-specific microarrays
Introns interrupt almost every eukaryotic protein-coding gene, yet how the splicing apparatus
interprets the genome during messenger RNA (mRNA) synthesis is poorly understood. We …
interprets the genome during messenger RNA (mRNA) synthesis is poorly understood. We …
[PDF][PDF] Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins
Understanding how RNA binding proteins control the splicing code is fundamental to
human biology and disease. Here, we present a comprehensive study to elucidate how …
human biology and disease. Here, we present a comprehensive study to elucidate how …
RBPmap: a web server for mapping binding sites of RNA-binding proteins
Regulation of gene expression is executed in many cases by RNA-binding proteins (RBPs)
that bind to mRNAs as well as to non-coding RNAs. RBPs recognize their RNA target via …
that bind to mRNAs as well as to non-coding RNAs. RBPs recognize their RNA target via …
Genome-wide bioinformatic and molecular analysis of introns in Saccharomyces cerevisiae
M Spingola, L Grate, D Haussler, M Ares - Rna, 1999 - cambridge.org
Introns have typically been discovered in an ad hoc fashion: introns are found as a gene is
characterized for other reasons. As complete eukaryotic genome sequences become …
characterized for other reasons. As complete eukaryotic genome sequences become …