Genetic and environmental factors produce different levels of DNA damage in spermatozoa.
Usually, DNA-fragmented spermatozoa (DFS) are used with intracytoplasmic sperm …

Waardenburg syndrome (WS; deafness with pigmentary abnormalities) is a congenital
disorder caused by defective function of the embryonic neural crest. Depending on additional …

Shugoshin-2 (SGOL2) is one of the two mammalian orthologs of the Shugoshin/Mei-S322
family of proteins that regulate sister chromatid cohesion by protecting the integrity of the …

The cohesin complex is a ring‐shaped proteinaceous structure that entraps the two sister
chromatids after replication until the onset of anaphase when the ring is opened by proteolytic …

Newly growing evidence highlights the essential role that epitranscriptomic marks play in
the development of many cancers; however, little is known about the role and implications of …

Slug is a zinc‐finger neural crest transcription factor, encoded by the SLUG gene, which is
critical for development of hematopoietic stem cells, germ cells, and melanoblasts in the …

In human cancers, all cancerous cells carry the oncogenic genetic lesions. However, to
elucidate whether cancer is a stem cell‐driven tissue, we have developed a strategy to limit …

Cohesin is a conserved multisubunit protein complex that participates in chromosome
segregation, DNA damage repair, chromatin regulation, and synaptonemal complex (SC) …

The SNAIL-related zinc-finger transcription factor, SLUG (SNAI2), is critical for the normal
development of neural crest-derived cells and loss-of-function SLUG mutations have been …

The stem cell factor c-kit signaling pathway (SCF/c-kit) has been previously implicated in
normal hematopoiesis, melanogenesis, and gametogenesis through the formation and …