Macrophages inhibit Coxiella burnetii by the ACOD1‐itaconate pathway for containment of Q fever
…, KT Yang, I Hayek, M Szperlinski… - EMBO Molecular …, 2023 - embopress.org
Infection with the intracellular bacterium Coxiella (C.) burnetii can cause chronic Q fever
with severe complications and limited treatment options. Here, we identify the enzyme cis‐…
with severe complications and limited treatment options. Here, we identify the enzyme cis‐…
[HTML][HTML] Cucumber gibberellin 1-oxidase/desaturase initiates novel gibberellin catabolic pathways
Bioactive gibberellins (GAs) are central regulators of plant growth and development, including
seed development. GA homeostasis is achieved via complex biosynthetic and catabolic …
seed development. GA homeostasis is achieved via complex biosynthetic and catabolic …
[HTML][HTML] Coxiella burnetii affects HIF1α accumulation and HIF1α target gene expression
I Hayek, M Szperlinski, A Lührmann - Frontiers in Cellular and …, 2022 - frontiersin.org
HIF1α is an important transcription factor regulating not only cellular responses to hypoxia,
but also anti-infective defense responses. We recently showed that HIF1α hampers …
but also anti-infective defense responses. We recently showed that HIF1α hampers …
Coxiella burnetii Affects HIF1a Accumulation and HIF1a Target Gene Expression
I Hayek, M Szperlinski… - Front. Cell. Infect. Microbiol …, 2022 - books.google.com
HIF1α is an important transcription factor regulating not only cellular responses to hypoxia,
but also anti-infective defense responses. We recently showed that HIF1α hampers …
but also anti-infective defense responses. We recently showed that HIF1α hampers …
The class III gibberellin 2-oxidases AtGA2ox9 and AtGA2ox10 contribute to cold stress tolerance and fertility
T Lange, C Krämer, MJ Pimenta Lange - Plant physiology, 2020 - academic.oup.com
… We thank Nils Kappe and Manuela Szperlinski for help with the characterization of GA2ox7
and maintenance of transgenic plants, respectively, Anja Liebrandt for technical assistance, …
and maintenance of transgenic plants, respectively, Anja Liebrandt for technical assistance, …
Ankyrin repeat proteins comprise a diverse family of bacterial type IV effectors
X Pan, A Luhrmann, A Satoh, MA Laskowski-Arce… - Science, 2008 - science.org
Specialized secretion systems are used by many bacteria to deliver effector proteins into
host cells that can either mimic or disrupt the function of eukaryotic factors. We found that the …
host cells that can either mimic or disrupt the function of eukaryotic factors. We found that the …
Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair
M Ruetz, GC Campanello, M Purchal, H Shen… - Science, 2019 - science.org
Itaconate is an immunometabolite with both anti-inflammatory and bactericidal effects. Its
coenzyme A (CoA) derivative, itaconyl-CoA, inhibits B 12 -dependent methylmalonyl-CoA …
coenzyme A (CoA) derivative, itaconyl-CoA, inhibits B 12 -dependent methylmalonyl-CoA …
Itaconate is an effector of a Rab GTPase cell-autonomous host defense pathway against Salmonella
The guanosine triphosphatase (GTPase) Rab32 coordinates a cell-intrinsic host defense
mechanism that restricts the replication of intravacuolar pathogens such as Salmonella. Here, …
mechanism that restricts the replication of intravacuolar pathogens such as Salmonella. Here, …
[HTML][HTML] Fadil, Fadi, Samol, Claudia, Berger, Raffaela S., Kellermeier, Fabian, Gronwald, Wolfram, Oefner, Peter J. und Dettmer, Katja (2023) Data archive of" Isotope …
UR Startseite, B nach Institutionen, B nach Projekten… - epub.uni-regensburg.de
Publikationen von 0000-0001-7337-2380 (ORCID: 0000-0001-7337-2380) - Publikationsserver
der Universität Regensburg Navigation Forschung Studium Netzwerke International …
der Universität Regensburg Navigation Forschung Studium Netzwerke International …