Lung granulomas develop upon Mycobacterium tuberculosis (Mtb) infection as a hallmark
of human tuberculosis (TB). They are structured aggregates consisting mainly of Mtb-infected …

Although hatching from eggs is fundamental for nematode biology it remains poorly understood.
For animal-parasitic nematodes in particular, advancement has been slow since the …

Organoids are multicellular culture systems that replicate tissue architecture and function,
and are increasingly used as models of viral, bacterial, and protozoan infections. Organoids …

As a hallmark of tuberculosis (TB), Mycobacterium tuberculosis (MTB) induces granulomatous
lung lesions and systemic inflammatory responses during active disease. Molecular …

The molecular basis of pathogen-induced host cell apoptosis is well characterized for a number
of microorganisms. Mycobacterium tuberculosis is known to induce apoptosis and it was …

Whole-genome sequencing is being rapidly applied to the study of helminth genomes, including
de novo genome assembly, population genetics, and diagnostic applications. Although …

The whipworm Trichuris trichiura is a soil-transmitted helminth that dwells in the epithelium
of the caecum and proximal colon of their hosts causing the human disease, trichuriasis. …

The caecum, an intestinal appendage in the junction of the small and large intestines, displays
a unique epithelium that serves as an exclusive niche for a range of pathogens including …

An often-stated ecomorphological assumption that has the status of ‘textbook knowledge’ is
that the dimensions of the digestive tract correlate with diet, where herbivores—consuming …

Whipworms are large metazoan parasites that inhabit multi-intracellular epithelial tunnels in
the large intestine of their hosts, causing chronic disease in humans and other mammals. …