Toward a systems approach to cytochrome P450 ensemble: interactions of CYP2E1 with other P450 species and their impact on CYP1A2

NY Davydova, B Dangi, MA Maldonado… - Biochemical …, 2019 - portlandpress.com
In this study, we investigate the ability of ethanol-inducible CYP2E1 to interact with other
cytochrome P450 species and affect the metabolism of their substrates. As a model system, we …

Effects of alcohol-induced increase in CYP2E1 content in human liver microsomes on the activity and cooperativity of CYP3A4

B Dangi, NY Davydova, MA Maldonado… - Archives of biochemistry …, 2021 - Elsevier
We investigate the effect of the alcohol-induced increase in the content of CYP2E1 in human
liver microsomes (HLM) on the function of CYP3A4. Membrane incorporation of the purified …

Probing functional interactions between cytochromes P450 with principal component analysis of substrate saturation profiles and targeted proteomics

B Dangi, NY Davydova, MA Maldonado, D Ahire… - Archives of biochemistry …, 2021 - Elsevier
We investigated the correspondence between drug metabolism routes and the composition
of the P450 ensemble in human liver microsomes (HLM). As a probe, we used Coumarin …

Comparison of intramolecular and intermolecular ammonium and phosphonium borohydrides in hydrogen‐, proton‐, and hydride‐transfer reactions

AP Lathem, BL Rinne, MA Maldonado… - European Journal of …, 2017 - Wiley Online Library
In this computational study, the thermodynamics of H 2 , proton, and hydride transfer from
13 ammonium borohydride and six phosphonium borohydride intramolecular and …

Non-additive effects of changing the cytochrome P450 ensemble: incorporation of CYP2E1 into human liver microsomes and its impact on CYP1A2

NY Davydova, B Dangi, MA Maldonado, NE Vavvlov… - bioRxiv, 2019 - biorxiv.org
The aim of this study is to investigate the ability of ethanol-inducible CYP2E1 to interact with
other cytochrome P450 species and affect the metabolism of their substrates. As a model …

Propagation of vibrations due to a tramway line

M Maldonado, O Chiello, D Le Houedec - Noise and Vibration Mitigation …, 2008 - Springer
Tramway traffic may produce vibrations propagating in soil leading to vibration annoyance
for people living or working in neighbouring buildings. Thus vibration is an important …

Interaction véhicule-voie-sol et vibrations dues aux trains: Modélisations et vérifications expérimentales

L Auersch, M Maldonado - European Journal of Computational …, 2011 - Taylor & Francis
This contribution presents models that are necessary to calculate the vibrations due to the
passage of a train. The models allow to calculate the propagation of the waves and the …

Differences in CAHPS adult survey reports and ratings by race and ethnicity: an analysis of the National CAHPS benchmarking data 1.0.

…, MN Elliott, R Weech-Maldonado… - Health Services …, 2001 - ncbi.nlm.nih.gov
OBJECTIVE: To examine racial/ethnic group differences in adults' reports and ratings of
care using data from the National Consumer Assessment of Health Plans (CAHPS) survey …

Dynamic wheel/rail forces induced by trams at low frequencies

O Chiello, M Maldonado - The Journal of the Acoustical Society of …, 2008 - pubs.aip.org
This work is part of various experimental and theoretical investigations into the noise and
the vibrations caused by trams in Nantes, France. It focuses on the problem of the low …

Modeling on-line search behavior using alternative output structures

ML Resnick, C Maldonado… - Proceedings of the …, 2001 - journals.sagepub.com
The Internet provides a fantastic opportunity for users to obtain information for which they
would otherwise have no access. However the existence of billions of web pages presents as …