This review discusses the impact of recent publications on pathophysiologic concepts and
on practical aspects of acute mountain sickness (AMS). Magnetic resonance imaging studies …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection induces a T cell
response that most likely contributes to virus control in COVID-19 patients but may also …

Rationale: High-altitude pulmonary edema (HAPE) is characterized by excessive pulmonary
vasoconstriction and is associated with decreased concentrations of nitric oxide (NO) in the …

High altitude (HA)‐induced pulmonary hypertension may be due to a free radical‐mediated
reduction in pulmonary nitric oxide (NO) bioavailability. We hypothesised that the increase in …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a worldwide health threat.
In a prospective multicentric study, we identify IL-3 as an independent prognostic marker …

Background Mitochondrial large-conductance Ca 2+ -sensitive potassium (mBK Ca )
channels are involved in myocardial ischemic preconditioning. Their role in sildenafil-induced …

… Two to four weeks following baseline evaluation at 110 m (Heidelberg, Germany), subjects
ascended in less than 24 h from 1130 m to the Margherita Hut (altitude, 4559 m), with a …

Decreased oxygen saturation (SO 2 ) at high altitude is associated with potentially life-threatening
diseases, eg, high-altitude pulmonary edema. Wearable devices that allow continuous …

The alpha-2 receptor agonist Dexmedetomidine (Dex) protects the heart against ischemia–reperfusion
injury. We investigated the signaling cascade underlying Dex-induced acute …

Acute mountain sickness (AMS) is a syndrome of nonspecific symptoms (ie, headache,
anorexia, nausea, vomiting, dizziness, and fatigue) that may develop in nonacclimatized …