User profiles for Marcel A. Müller

Marcel A. Müller

Professor, Institute of Virology, Charité Universitätsmedizin Berlin
Verified email at charite.de
Cited by 57619

[PDF][PDF] SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor

…, G Herrler, NH Wu, A Nitsche, MA Müller… - cell, 2020 - cell.com
The recent emergence of the novel, pathogenic SARS-coronavirus 2 (SARS-CoV-2) in China
and its rapid national and international spread pose a global health emergency. Cell entry …

[HTML][HTML] Virological assessment of hospitalized patients with COVID-2019

…, W Guggemos, M Seilmaier, S Zange, MA Müller… - Nature, 2020 - nature.com
Coronavirus disease 2019 (COVID-19) is an acute infection of the respiratory tract that emerged
in late 2019 1 , 2 . Initial outbreaks in China involved 13.8% of cases with severe courses…

[HTML][HTML] SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19

…, S Voigt, J Schmitz, S Miltenyi, I Demuth, MA Müller… - Nature, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the rapidly
unfolding coronavirus disease 2019 (COVID-19) pandemic 1, 2. Clinical manifestations of …

[HTML][HTML] Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC

VS Raj, H Mou, SL Smits, DHW Dekkers, MA Müller… - Nature, 2013 - nature.com
Most human coronaviruses cause mild upper respiratory tract disease but may be associated
with more severe pulmonary disease in immunocompromised individuals 1 . However, …

[HTML][HTML] Severe acute respiratory syndrome coronavirus 2− specific antibody responses in coronavirus disease patients

NMA Okba, MA Müller, W Li, C Wang… - Emerging infectious …, 2020 - ncbi.nlm.nih.gov
A new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has
recently emerged to cause a human pandemic. Although molecular diagnostic tests were …

Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral …

I Glowacka, S Bertram, MA Müller, P Allen… - Journal of …, 2011 - Am Soc Microbiol
The spike (S) protein of the severe acute respiratory syndrome coronavirus (SARS-CoV)
can be proteolytically activated by cathepsins B and L upon viral uptake into target cell …

[HTML][HTML] Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study

CBEM Reusken, BL Haagmans, MA Müller… - The Lancet infectious …, 2013 - thelancet.com
Background A new betacoronavirus—Middle East respiratory syndrome coronavirus (MERS-CoV)—has
been identified in patients with severe acute respiratory infection. Although …

[HTML][HTML] Nafamostat mesylate blocks activation of SARS-CoV-2: new treatment option for COVID-19

…, S Schroeder, H Kleine-Weber, MA Müller… - Antimicrobial agents …, 2020 - Am Soc Microbiol
The currently unfolding coronavirus pandemic threatens health systems and economies
worldwide. The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and …

[HTML][HTML] Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2

…, H Kleine-Weber, N Krüger, NC Gassen, MA Müller… - Nature, 2020 - nature.com
The coronavirus disease 2019 (COVID-19) pandemic, which is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has been associated with more than …

[HTML][HTML] Bats host major mammalian paramyxoviruses

JF Drexler, VM Corman, MA Müller… - Nature …, 2012 - nature.com
The large virus family Paramyxoviridae includes some of the most significant human and
livestock viruses, such as measles-, distemper-, mumps-, parainfluenza-, Newcastle disease-, …