The dependence of development and homeostasis in animals on the interaction of hundreds
of extracellular regulatory proteins with the peri- and extracellular glycosaminoglycan …

Heparan sulfate (HS) polysaccharides are ubiquitous components of the cell surface and
extracellular matrix of all multicellular animals, whereas heparin is present within mast cells …

Depression is a frequently encountered non-motor feature of Parkinson's disease (PD) and
it can have a significant impact on patient's quality of life. Considering the differential …

Parkinson’s disease (PD) is the second most common neurodegenerative disorder affecting
about 1% of the population older than 60 years. Classically, PD is considered as a …

Recent evidence has demonstrated dietary influence on the manifestation of different types
of behaviors induced by stressor tasks. The present study examined the impact of ω-3 …

Background and Purpose Currently, there are no licensed vaccines and limited antivirals for
the treatment of COVID‐19. Heparin (delivered systemically) is currently used to treat …

Epidemiological and dietary studies show that nutritional deficit of omega-3 polyunsaturated
fatty acids (ω-3 PUFA) is directly related to the prevalence and severity of depression. …

Objective Shift work is associated with circadian rhythm disorder, impaired sleep and behavioural
changes, including eating habits, predisposing to obesity and metabolic dysfunctions. …

Heparan sulfate (HS) is a cell surface polysaccharide recently identified as a coreceptor with
the ACE2 protein for the S1 spike protein on SARS-CoV-2 virus, providing a tractable new …

Nearly all patients with Parkinson's disease (PD) have sleep disturbances. While it has
been suggested that these disturbances involve a dopaminergic component, the specific …