User profiles for Marco Antonio Mendoza-Parra
Marco Antonio Mendoza ParraCNRS Verified email at genoscope.cns.fr Cited by 2523 |
Senescence-associated reprogramming promotes cancer stemness
…, D Lenze, IA Monteiro Barbosa, MA Mendoza-Parra… - Nature, 2018 - nature.com
Cellular senescence is a stress-responsive cell-cycle arrest program that terminates the
further expansion of (pre-)malignant cells 1 , 2 . Key signalling components of the senescence …
further expansion of (pre-)malignant cells 1 , 2 . Key signalling components of the senescence …
The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer
Disappearance of the Barr body is considered a hallmark of cancer, although whether this
corresponds to genetic loss or to epigenetic instability and transcriptional reactivation is …
corresponds to genetic loss or to epigenetic instability and transcriptional reactivation is …
Single-tube linear DNA amplification (LinDA) for robust ChIP-seq
P Shankaranarayanan, MA Mendoza-Parra, M Walia… - Nature …, 2011 - nature.com
Genome-wide profiling of transcription factors based on massive parallel sequencing of
immunoprecipitated chromatin (ChIP-seq) requires nanogram amounts of DNA. Here we …
immunoprecipitated chromatin (ChIP-seq) requires nanogram amounts of DNA. Here we …
Dissecting the retinoid‐induced differentiation of F9 embryonal stem cells by integrative genomics
MA Mendoza‐Parra, M Walia, M Sankar… - Molecular systems …, 2011 - embopress.org
Retinoic acid (RA) triggers physiological processes by activating heterodimeric transcription
factors (TFs) comprising retinoic acid receptor (RARα, β, γ) and retinoid X receptor (RXRα, β…
factors (TFs) comprising retinoic acid receptor (RARα, β, γ) and retinoid X receptor (RXRα, β…
[PDF][PDF] Inferring biologically relevant molecular tissue substructures by agglomerative clustering of digitized spatial transcriptomes with multilayer
J Moehlin, B Mollet, BM Colombo, MA Mendoza-Parra - Cell Systems, 2021 - cell.com
Spatially resolved transcriptomics (SrT) can investigate organ or tissue architecture from the
angle of gene programs that define their molecular complexity. However, computational …
angle of gene programs that define their molecular complexity. However, computational …
A quality control system for profiles obtained by ChIP sequencing
MA Mendoza-Parra, W Van Gool… - Nucleic acids …, 2013 - academic.oup.com
The absence of a quality control (QC) system is a major weakness for the comparative analysis
of genome-wide profiles generated by next-generation sequencing (NGS). This concerns …
of genome-wide profiles generated by next-generation sequencing (NGS). This concerns …
[HTML][HTML] CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity
The acetyltransferases CBP and P300 have been implicated in myogenesis in mouse
immortalized cell lines but these studies focused only on the expression of a handful of myogenic …
immortalized cell lines but these studies focused only on the expression of a handful of myogenic …
[HTML][HTML] Real-time SARS-CoV-2 diagnostic and variants tracking over multiple candidates using nanopore DNA sequencing
F Stüder, JL Petit, S Engelen, MA Mendoza-Parra - Scientific reports, 2021 - nature.com
Since December 2019, a novel coronavirus responsible for a severe acute respiratory syndrome
(SARS-CoV-2) is accountable for a major pandemic situation. The emergence of the B.…
(SARS-CoV-2) is accountable for a major pandemic situation. The emergence of the B.…
Reconstructed cell fate–regulatory programs in stem cells reveal hierarchies and key factors of neurogenesis
MA Mendoza-Parra, V Malysheva… - Genome …, 2016 - genome.cshlp.org
Cell lineages, which shape the body architecture and specify cell functions, derive from the
integration of a plethora of cell intrinsic and extrinsic signals. These signals trigger a …
integration of a plethora of cell intrinsic and extrinsic signals. These signals trigger a …
[PDF][PDF] Three-dimensional molecular cartography of human cerebral organoids revealed by double-barcoded spatial transcriptomics
…, F Yates, JP Deslys, MA Mendoza-Parra - Cell Reports …, 2023 - cell.com
Spatially resolved transcriptomics is revolutionizing our understanding of complex tissues,
but scaling these approaches to multiple tissue sections and three-dimensional tissue …
but scaling these approaches to multiple tissue sections and three-dimensional tissue …