Regulation of the unfolded protein response in yeast by oxidative stress

A Guerra‐Moreno, J Ang, H Welsch, M Jochem… - FEBS …, 2019 - Wiley Online Library
In the unfolded protein response ( UPR ), Ire1 activates Hac1 to coordinate the transcription
of hundreds of genes to mitigate ER stress. Recent work in Caenorhabditis elegans …

Targeted degradation of glucose transporters protects against arsenic toxicity

M Jochem, L Ende, M Isasa, J Ang… - … and Cellular Biology, 2019 - Taylor & Francis
The abundance of cell surface glucose transporters must be precisely regulated to ensure
optimal growth under constantly changing environmental conditions. We recently conducted a …

Translational activity controls ribophagic flux and turnover of distinct ribosome pools

J Trendel, M Aleksić, M Bertolini, M Jochem, G Kramer… - bioRxiv, 2022 - biorxiv.org
Ribosomes are among the most abundant and complex machineries in the cell, however,
the turnover of their subunits remains poorly understood. Here, we apply proteomic flux and …

Reg1 and Snf1 regulate stress‐induced relocalization of protein phosphatase‐1 to cytoplasmic granules

HM Schnell, M Jochem, Y Micoogullari… - The FEBS …, 2021 - Wiley Online Library
The compartmentalization of cellular function is achieved largely through the existence of
membrane‐bound organelles. However, recent work suggests a novel mechanism of …

Degradome analysis to identify direct protein substrates of small-molecule degraders

M Jochem, A Schrempf, LM Wagner, J Cisneros, A Ng… - bioRxiv, 2024 - biorxiv.org
Targeted protein degradation (TPD) has emerged as a powerful strategy to selectively
eliminate cellular proteins using small-molecule degraders, offering therapeutic promise for …

PEPseq quantifies transcriptome-wide changes in protein occupancy and reveals selective translational repression after translational stress

J Trendel, E Boileau, M Jochem… - Nucleic Acids …, 2023 - academic.oup.com
Post-transcriptional gene regulation is accomplished by the interplay of the transcriptome
with RNA-binding proteins, which occurs in a dynamic manner in response to altered cellular …

[HTML][HTML] Boosting the predictive accuracy of urban hedonic house price models through airborne laser scanning

M Helbich, A Jochem, W Mücke, B Höfle - Computers, environment and …, 2013 - Elsevier
This paper introduces an integrative approach to hedonic house price modeling which utilizes
high density 3D airborne laser scanning (ALS) data. In general, it is shown that extracting …

[PDF][PDF] Com puters, Environ ment and Urban System s

M Helbich, A Jochem, W Mücke… - … , Environment and Urban …, 2013 - cyberleninka.org
This paper introduces an integrati ve approach to hedonic house price modeling which utilizes
high density 3D airborne laser scanning (ALS) data. In general, it is shown that extracting …

[BOOK][B] Enterprise Inter-and Intra-Organizational Integration: Building International Consensus

K Kosanke, R Jochem, JG Nell, AO Bas - 2002 - books.google.com
The international initiative on Enterprise Inter-and Intra-Organisational Integration (EI3-IC)
had the objective to increase both international consen sus (IC) and public awareness on …

[PDF][PDF] Joanne M. van der Velden1, Helena M. Verkooijen1, 2, Enrica Seravalli1, Jochem Hes1, A. Sophie Gerlich1

N Kasperts, WSC Eppinga, JJ Verlaan… - 2016 - bmccancer.biomedcentral.com
Methods/design Study design This study is conducted within the Prospective Evaluation of
interventional StudiEs on boNe meTastases (PRESENT) cohort [12]. All patients with bone …