User profiles for Marcus E. Peter
 | Marcus E. PeterNorthwestern University Verified email at northwestern.edu Cited by 75653 |
[HTML][HTML] Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical, …
guidelines for the definition and interpretation of cell death from morphological, biochemical, …
Apoptosis signaling by death receptors
…, M Los, S Wesselborg, ME Peter - European journal of …, 1998 - Wiley Online Library
Death receptors have been recently identified as a subgroup of the TNF‐receptor superfamily
with a predominant function in induction of apoptosis. The receptors are characterized by …
with a predominant function in induction of apoptosis. The receptors are characterized by …
[HTML][HTML] Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes
Cell death is essential for a plethora of physiological processes, and its deregulation
characterizes numerous human diseases. Thus, the in-depth investigation of cell death and its …
characterizes numerous human diseases. Thus, the in-depth investigation of cell death and its …
[HTML][HTML] FLICE, a novel FADD-homologous ICE/CED-3–like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
To identify CAP3 and CAP4, components of the CD95 (Fas/APO-1) death-inducing signaling
complex, we utilized nano-electrospray tandem mass spectrometry, a recently developed …
complex, we utilized nano-electrospray tandem mass spectrometry, a recently developed …
[HTML][HTML] Two CD95 (APO-1/Fas) signaling pathways
…, KM Debatin, PH Krammer, ME Peter - The EMBO …, 1998 - embopress.org
We have identified two cell types, each using almost exclusively one of two different CD95 (APO-1/Fas)
signaling pathways. In type I cells, caspase-8 was activated within seconds and …
signaling pathways. In type I cells, caspase-8 was activated within seconds and …
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
Cancer progression has similarities with the process of epithelial-to-mesenchymal transition
(EMT) found during embryonic development, during which cells down-regulate E-cadherin …
(EMT) found during embryonic development, during which cells down-regulate E-cadherin …
Cytotoxicity‐dependent APO‐1 (Fas/CD95)‐associated proteins form a death‐inducing signaling complex (DISC) with the receptor.
…, M Germer, M Pawlita, PH Krammer, ME Peter - The EMBO …, 1995 - embopress.org
APO‐1 (Fas/CD95), a member of the tumor necrosis factor receptor superfamily, induces
apoptosis upon receptor oligomerization. In a search to identify intracellular signaling …
apoptosis upon receptor oligomerization. In a search to identify intracellular signaling …
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
Intra-abdominal tumors, such as ovarian cancer 1 , 2 , have a clear predilection for metastasis
to the omentum, an organ primarily composed of adipocytes. Currently, it is unclear why …
to the omentum, an organ primarily composed of adipocytes. Currently, it is unclear why …
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
Viruses have evolved many distinct strategies to avoid the host's apoptotic response 1,2 .
Here we describe a new family of viral inhibitors (v-FLIPs) which interfere with apoptosis …
Here we describe a new family of viral inhibitors (v-FLIPs) which interfere with apoptosis …
[HTML][HTML] FLICE is activated by association with the CD95 death‐inducing signaling complex (DISC)
Upon activation, the apoptosis‐inducing cell membrane receptor CD95 (APO‐1/Fas) recruits
a set of intracellular signaling proteins (CAP1‐4) into a death‐inducing signaling complex (…
a set of intracellular signaling proteins (CAP1‐4) into a death‐inducing signaling complex (…