Background Steroid use for coronavirus disease 2019 (COVID-19) is based on the possible
role of these drugs in mitigating the inflammatory response, mainly in the lungs, triggered by …

Importance There is no specific antiviral therapy recommended for coronavirus disease 2019
(COVID-19). In vitro studies indicate that the antiviral effect of chloroquine diphosphate (CQ…

Malaria is still a major public health problem in Brazil, with approximately 306 000 registered
cases in 2009, but it is estimated that in the early 1940s, around six million cases of malaria …

Background Recent gains in reducing the global burden of malaria are threatened by the
emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations …

Background. Plasmodium falciparum and Plasmodium vivax are responsible for most of the
global burden of malaria. Although the accentuated pathogenicity of P. falciparum occurs …

The outbreak of new coronavirus disease 2019 (COVID-19) reported for the first time in Wuhan,
China in late December 2019 have rapidly spread to other countries and it was declared …

Background: Steroid use for COVID-19 is based on the possible role of these drugs in
mitigating the inflammatory response, mainly in the lungs, triggered by SARS-CoV-2. This study …

Background Clinical effectiveness of previous regimens to treat Plasmodium vivax infection
have been hampered by compliance. We aimed to assess the dose–response, safety, and …

Despite not being a criterion for severe malaria, thrombocytopenia is one of the most
common complications of both Plasmodium vivax and Plasmodium falciparum malaria. In a …

In spite of significant progress towards malaria control and elimination achieved in South
America in the 2000s, this mosquito-transmitted tropical disease remains an important public …