The two-feedback-loop regulatory module of nuclear factor κB (NF-κB) signaling pathway is
modeled by means of ordinary differential equations. The constructed model involves two-…

Using the generalized stepwise mutation model, we propose a method of estimating the relative
mutation rates of microsatellite loci, grouped by the repeat motif. Applying ANOVA to the …

We present the codimensional principal component analysis (PCA), a novel and straightforward
method for resolving sample heterogeneity within a set of cryo-EM 2D projection images …

Functional sites determine the activity and interactions of proteins and as such constitute the
targets of most drugs. However, the exponential growth of sequence and structure data far …

The sensitivity of voided urinary cytology (VUC), bladder wash cytology (BWC), and bladder
wash flow cytometry (BWFCM) in detecting cancer was studied in 70 patients with biopsy‐…

Oligonucleotide microarrays belong to the basic tools of molecular biology and allow for
simultaneous assessment of the expression level of thousands of genes. Analysis of microarray …

In the period from 1923 to 1986 our pathologists examined pathologic material from 102
patients with alveolar soft‐part sarcoma (ASPS). Followup clinical data is available for 91. …

We investigate the qualitative behaviour of the models of cell production systems, in the form
of systems of nonlinear delay differential equations. Considered are three general models …

Age-related clonal hematopoiesis (CH) is a risk factor for malignancy, cardiovascular disease,
and all-cause mortality. Somatic mutations in DNMT3A are drivers of CH, but decades …

We assessed the effect of surgery on survival from stage I non-small-cell lung cancer based
on data collected in these screening programs. The majority of patients diagnosed in each …