[HTML][HTML] The type III secretion effector NleE inhibits NF-κB activation

…, K Baruch, S Kobi, E Mills, G Haviv, M Farago… - PLoS …, 2010 - journals.plos.org
The complex host-pathogen interplay involves the recognition of the pathogen by the host's
innate immune system and countermeasures taken by the pathogen. Detection of invading …

Oncogenic signaling pathways activated in DMBA-induced mouse mammary tumors

…, EG Demicco, DLF Chang, M Farago… - Toxicologic …, 2005 - journals.sagepub.com
Only about 5% of human breast cancers can be attributed to inheritance of breast cancer
susceptibility genes, while the balance are considered to be sporadic in origin. Breast cancer …

Kinase-inactive glycogen synthase kinase 3β promotes Wnt signaling and mammary tumorigenesis

M Farago, I Dominguez, E Landesman-Bollag, X Xu… - Cancer research, 2005 - AACR
Recent studies have implicated ectopic activation of the Wnt pathway in many human cancers,
including breast cancer. β-catenin is a critical coactivator in this signaling pathway and is …

CK2 as a positive regulator of Wnt signalling and tumourigenesis

DC Seldin, E Landesman-Bollag, M Farago… - Molecular and cellular …, 2005 - Springer
CK2 is upregulated in rapidly dividing cells including most human tumours. Transgenic
overexpression of CK2 in lymphoid or mammary lineages predisposes to transformation. Multiple …

A role for the aryl hydrocarbon receptor in mammary gland tumorigenesis

JJ Schlezinger, D Liu, M Farago, DC Seldin, K Belguise… - 2006 - degruyter.com
The aryl hydrocarbon receptor (AhR) is an evolutionarily conserved transcription factor
bound and activated by ubiquitous environmental pollutants. Historically, the AhR has been …

Oct‐3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β‐catenin signalling

M Abu‐Remaileh, A Gerson, M Farago, G Nathan… - The EMBO …, 2010 - embopress.org
Although the transcriptional regulatory events triggered by Oct‐3/4 are well documented,
understanding the proteomic networks that mediate the diverse functions of this POU domain …

GTP exchange factor Vav regulates guided cell migration by coupling guidance receptor signalling to local Rac activation

…, D Ramel, M Farago… - Journal of cell …, 2013 - journals.biologists.com
Guided cell migration is a key mechanism for cell positioning in morphogenesis. The current
model suggests that the spatially controlled activation of receptor tyrosine kinases (RTKs) …

Rpb4p, a subunit of RNA polymerase II, mediates mRNA export during stress

M Farago, T Nahari, C Hammel, CN Cole… - Molecular biology of …, 2003 - Am Soc Cell Biol
Changes in gene expression represent a major mechanism by which cells respond to stress.
We and other investigators have previously shown that the yeast RNA polymerase II …

Germline DNA replication timing shapes mammalian genome composition

…, S Baror-Sebban, H Masika, M Farago… - Nucleic acids …, 2018 - academic.oup.com
Mammalian DNA replication is a highly organized and regulated process. Large, Mb-sized
regions are replicated at defined times along S-phase. Replication Timing (RT) is thought to …

Direct detection and quantitation of a distinct T-cell epitope derived from tumor-specific epithelial cell-associated mucin using human recombinant antibodies endowed …

CJ Cohen, N Hoffmann, M Farago, HR Hoogenboom… - Cancer research, 2002 - AACR
The recent characterization of MHC-displayed tumor-associated antigens that recognize
effector cells of the immune system has created new perspectives for cancer therapy. …