User profiles for Margaret A. Richter
Margaret A. RichterAssociate Professor of Psychiatry, University of Toronto Verified email at sunnybrook.ca Cited by 13492 |
[HTML][HTML] Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder
A functional serotonin transporter promoter polymorphism, HTTLPR, alters the risk of disease
as well as brain morphometry and function. Here, we show that HTTLPR is functionally …
as well as brain morphometry and function. Here, we show that HTTLPR is functionally …
Symptom structure in obsessive-compulsive disorder: a confirmatory factor-analytic study
Although obsessive-compulsive disorder (OCD) has long been a unitary diagnosis, there is
much recent interest in its potential heterogeneity, as manifested by symptom subgroups. …
much recent interest in its potential heterogeneity, as manifested by symptom subgroups. …
Glutamate transporter gene SLC1A1 associated with obsessive-compulsive disorder
…, T Sicard, E Burroughs, MA Richter… - Archives of general …, 2006 - jamanetwork.com
Context There is strong evidence from family and twin studies that genetic determinants
play an important role in the etiology of obsessive-compulsive disorder (OCD). In the only …
play an important role in the etiology of obsessive-compulsive disorder (OCD). In the only …
Genome-wide association study of obsessive-compulsive disorder
…, M Wagner, L Bellodi, MC Cavallini, MA Richter… - Molecular …, 2013 - nature.com
Obsessive-compulsive disorder (OCD) is a common, debilitating neuropsychiatric illness
with complex genetic etiology. The International OCD Foundation Genetics Collaborative (…
with complex genetic etiology. The International OCD Foundation Genetics Collaborative (…
[HTML][HTML] Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture
The direct estimation of heritability from genome-wide common variant data as implemented
in the program Genome-wide Complex Trait Analysis (GCTA) has provided a means to …
in the program Genome-wide Complex Trait Analysis (GCTA) has provided a means to …
Association of a glutamate (NMDA) subunit receptor gene (GRIN2B) with obsessive-compulsive disorder: a preliminary study
…, S Tharmalingam, JL Kennedy, MA Richter - …, 2004 - Springer
Rationale Recent investigation suggests that a reversible glutamatergically mediated
thalamocortical-striatal dysfunction may serve as a reliable pathophysiological and treatment …
thalamocortical-striatal dysfunction may serve as a reliable pathophysiological and treatment …
Comorbidity and pathophysiology of obsessive–compulsive disorder in schizophrenia: is there evidence for a schizo-obsessive subtype of schizophrenia?
A Bottas, RG Cooke, MA Richter - Journal of Psychiatry and Neuroscience, 2005 - jpn.ca
Epidemiologic and neurobiologic evidence suggests that patients with comorbid obsessive–compulsive
disorder (OCD) and schizophrenia may represent a special category among …
disorder (OCD) and schizophrenia may represent a special category among …
Quality of life in OCD: differential impact of obsessions, compulsions, and depression comorbidity
…, NA Rector, MA Richter - The Canadian Journal of …, 2003 - journals.sagepub.com
Objective: An anxiety disorder severely affects the sufferer's quality of life (QOL), and this
may be particularly true of those with obsessive–compulsive disorder (OCD). This study …
may be particularly true of those with obsessive–compulsive disorder (OCD). This study …
Memory and confidence in memory judgments among individuals with obsessive compulsive disorder and non-clinical controls
The present study investigated episodic memory functioning in: (1) obsessive compulsive
disorder (OCD) patients with primarily checking symptoms (ie checkers); (2) OCD patients …
disorder (OCD) patients with primarily checking symptoms (ie checkers); (2) OCD patients …
Inflammation in the neurocircuitry of obsessive-compulsive disorder
…, R Mizrahi, L Miler, C Xu, MA Richter… - JAMA …, 2017 - jamanetwork.com
Importance For a small percentage of obsessive-compulsive disorder (OCD) cases exhibiting
additional neuropsychiatric symptoms, it was proposed that neuroinflammation occurs in …
additional neuropsychiatric symptoms, it was proposed that neuroinflammation occurs in …