Evidence on the human health effects of low-level methylmercury exposure

MR Karagas, AL Choi, E Oken, M Horvat… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: Methylmercury (MeHg) is a known neuro-toxicant. Emerging evidence indicates
it may have adverse effects on the neuro-logic and other body systems at common low …

Metals and trace elements in relation to body mass index in a prospective study of US women

…, AP Keil, KM O'brien, BP Jackson, MR Karagas… - Environmental …, 2020 - Elsevier
Background Epidemiologic studies on the association between metals and body mass index
(BMI) have been cross-sectional and have demonstrated inconsistent associations. Our …

Arsenic Exposure Is Associated with Decreased DNA Repair in Vitro and in Individuals Exposed to Drinking Water Arsenic

…, MG Waugh, JW Hamilton, MR Karagas - Environmental …, 2006 - ehp.niehs.nih.gov
The mechanism(s) by which arsenic exposure contributes to human cancer risk is unknown;
however, several indirect cocarcinogenesis mechanisms have been proposed. Many …

[HTML][HTML] Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context

…, JL Wiemels, HH Nelson, MR Karagas… - PLoS …, 2009 - journals.plos.org
Epigenetic control of gene transcription is critical for normal human development and cellular
differentiation. While alterations of epigenetic marks such as DNA methylation have been …

Risk of basal cell and squamous cell skin cancers after ionizing radiation therapy

MR Karagas, JA McDonald… - JNCI: Journal of the …, 1996 - academic.oup.com
Background Human evidence that ionizing radiation is carcinogenic first came from reports
of nonmelanoma skin cancers (NMSCs) on the hands of workers using early radiation …

New common variants affecting susceptibility to basal cell carcinoma

…, E Nagore, JI Mayordomo, R Kumar, MR Karagas… - Nature …, 2009 - nature.com
In a follow-up to our previously reported genome-wide association study of cutaneous basal
cell carcinoma (BCC) 1 , we describe here several new susceptibility variants. SNP …

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci

…, J Lloreta, A Johnson, M Schwenn, MR Karagas… - Nature …, 2010 - nature.com
We conducted a multi-stage, genome-wide association study of bladder cancer with a
primary scan of 591,637 SNPs in 3,532 affected individuals (cases) and 5,120 controls of …

DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma

…, JL Wiemels, HH Nelson, MR Karagas… - Journal of the …, 2011 - academic.oup.com
Background Although much is known about molecular and chromosomal characteristics
that distinguish glioma histological subtypes, DNA methylation patterns of gliomas and their …

Use of tanning devices and risk of basal cell and squamous cell skin cancers

MR Karagas, VA Stannard, LA Mott… - Journal of the …, 2002 - academic.oup.com
Use of artificial tanning devices that emit UV radiation, such as tanning lamps and tanning
beds, has become increasingly popular in the United States. Although an excess risk of …

Skin cancer risk in relation to toenail arsenic concentrations in a US population-based case-control study

MR Karagas, TA Stukel, JS Morris… - American journal of …, 2001 - academic.oup.com
Arsenic is a known carcinogen specifically linked to skin cancer occurrence in regions with
highly contaminated drinking water or in individuals who took arsenic-containing medicines. …