User profiles for Margaret L. MacMillan

Margaret L MacMillan

University of Minnesota
Verified email at umn.edu
Cited by 11871

Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on …

…, J Kersey, W Krivit, ML MacMillan… - Blood, The Journal …, 2002 - ashpublications.org
The potential benefits of unrelated donor marrow transplantation are offset by the immunologic
complications of graft-versus-host disease (GVHD) and infection. Therefore, we used …

Response of 443 patients to steroids as primary therapy for acute graft-versus-host disease: comparison of grading systems

ML MacMillan, DJ Weisdorf, JE Wagner… - Biology of blood and …, 2002 - tctjournal.org
Acute GVHD remains a major cause of morbidity and mortality after allogeneic hematopoietic
stem cell transplantation (HSCT). In a retrospective analysis, the response of 443 HSCT …

Composite end point of graft-versus-host disease-free, relapse-free survival after allogeneic hematopoietic cell transplantation

…, BR Blazar, ML MacMillan… - Blood, The Journal …, 2015 - ashpublications.org
The success of allogeneic hematopoietic cell transplantation (HCT) is typically assessed as
individual complications, including graft-versus-host disease (GVHD), relapse, or death, yet …

Umbilical cord blood–derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

…, MR Verneris, ML MacMillan… - Blood, The Journal …, 2016 - ashpublications.org
We studied the safety and clinical outcomes of patients treated with umbilical cord blood (UCB)-derived
regulatory T cells (Tregs) that expanded in cultures stimulated with K562 cells …

Relapse risk after umbilical cord blood transplantation: enhanced graft-versus-leukemia effect in recipients of 2 units

…, CG Brunstein, J Barker, ML MacMillan… - Blood, The Journal …, 2009 - ashpublications.org
Umbilical cord blood (UCB) transplantation is potentially curative for acute leukemia. This
analysis was performed to identify risk factors associated with leukemia relapse following …

[HTML][HTML] A refined risk score for acute graft-versus-host disease that predicts response to initial therapy, survival, and transplant-related mortality

ML MacMillan, M Robin, AC Harris, TE DeFor… - Biology of Blood and …, 2015 - Elsevier
To develop a novel acute graft-versus-host disease (GVHD) risk score, we examined the GVHD
clinical stage and grade of 1723 patients at the onset of treatment with systemic steroids. …

Acute graft-versus-host disease after unrelated donor umbilical cord blood transplantation: analysis of risk factors

ML MacMillan, DJ Weisdorf… - Blood, The Journal …, 2009 - ashpublications.org
Acute graft-versus-host disease (GVHD) occurs less frequently after umbilical cord blood
transplantation (UCBT). More recent investigations include the use of 2 partially human …

[HTML][HTML] Long-term results of autologous stem cell transplantation for primary refractory or relapsed Hodgkin's lymphoma

…, NKC Ramsay, PJ Orchard, ML MacMillan… - Biology of Blood and …, 2006 - Elsevier
Autologous hematopoietic stem cell transplantation (ASCT) has become standard therapy
for primary refractory (PR REF) or relapsed (REL) Hodgkin’s lymphoma (HL); however, more …

Germline mutations in BRCA2: shared genetic susceptibility to breast cancer, early onset leukemia, and Fanconi anemia

…, K Mah, SD Batish, DI Kutler, ML MacMillan… - Blood, 2004 - ashpublications.org
The breast cancer susceptibility gene BRCA2 has recently been identified as identical to the
Fanconi anemia (FA) gene FANCD1. Here we expand the clinical implications of this …

Tacrolimus/sirolimus vs tacrolimus/methotrexate as GVHD prophylaxis after matched, related donor allogeneic HCT

…, WJ Hogan, M Pasquini, ML MacMillan… - Blood, The Journal …, 2014 - ashpublications.org
Grades 2-4 acute graft-versus-host disease (GVHD) occurs in approximately 35% of matched,
related donor (MRD) allogeneic hematopoietic cell transplantation (HCT) recipients. We …