The basic helix–loop–helix transcription factors MYC1 and MYC2 have a dual role in the regulation of constitutive and stress‐inducible specialized metabolism in …

G Swinnen, M De Meyer, J Pollier… - New …, 2022 - Wiley Online Library
Plants produce specialized metabolites to protect themselves from biotic enemies. Members
of the Solanaceae family accumulate phenylpropanoid–polyamine conjugates (PPCs) in …

[HTML][HTML] Capturing Salmonella SspH2 Host Targets in Virus-Like Particles

M De Meyer, I Fijalkowski, V Jonckheere… - Frontiers in …, 2021 - frontiersin.org
In the context of host-pathogen interactions, gram-negative bacterial virulence factors, such
as effectors, may be transferred from bacterial to eukaryotic host cytoplasm by …

Constitutive steroidal glycoalkaloid biosynthesis in tomato is regulated by the clade IIIe basic helix-loop-helix transcription factors MYC1 and MYC2

G Swinnen, M De Meyer, J Pollier, FJ Molina-Hidalgo… - BioRxiv, 2020 - biorxiv.org
Specialized metabolites are produced by plants to fend off biotic enemies. Across the plant
kingdom, the biosynthesis of these defense compounds is promoted by jasmonate signaling …

Leveraging a self-cleaving peptide for tailored control in proximity labeling proteomics

…, A Verhee, D De Sutter, T Van de Steene, M De Meyer… - bioRxiv, 2023 - biorxiv.org
Protein-protein interactions play an important biological role in every aspect of cellular
homeostasis and functioning. Proximity labeling mass spectrometry-based proteomics overcomes …

[HTML][HTML] Keeping in touch with type-III secretion system effectors: mass spectrometry-based proteomics to study effector–host protein–protein interactions

MD Meyer, JD Ryck, S Goormachtig… - International journal of …, 2020 - mdpi.com
Manipulation of host cellular processes by translocated bacterial effectors is key to the success
of bacterial pathogens and some symbionts. Therefore, a comprehensive understanding …

[HTML][HTML] Shift in vacuolar to cytosolic regime of infecting Salmonella from a dual proteome perspective

U Fels, P Willems, M De Meyer, K Gevaert… - PLoS …, 2023 - journals.plos.org
By applying dual proteome profiling to Salmonella enterica serovar Typhimurium (S. Typhimurium)
encounters with its epithelial host (here, S. Typhimurium infected human HeLa cells), …

Virotrap: Trapping Protein Complexes in Virus-Like Particles

GD Moschonas, M De Meyer, D De Sutter… - Mass Spectrometry …, 2023 - Springer
The discovery of protein-protein interactions can provide crucial information on protein function
by linking proteins into known pathways or complexes within the cell. Mass spectrometry (…

Tau deletion promotes brain insulin resistance

…, K Bantubungi, S Lancel, D Demeyer… - Journal of Experimental …, 2017 - rupress.org
The molecular pathways underlying tau pathology–induced synaptic/cognitive deficits and
neurodegeneration are poorly understood. One prevalent hypothesis is that …

Analyses of thrombi in acute ischemic stroke: a consensus statement on current knowledge and future directions

SF De Meyer, T Andersson, B Baxter… - … journal of stroke, 2017 - journals.sagepub.com
Limited data exist on clot composition and detailed characteristics of arterial thrombi
associated with large vessel occlusion in acute ischemic stroke. Advances in endovascular …

Which factors contribute to sexual well-being? A comparative study among 17 to 20 year old boys and girls in Belgium and Ecuador

S De Meyer, E Jerves, A Cevallos-Neira… - Culture, Health & …, 2022 - Taylor & Francis
Despite recognition that sexual well-being is an important part of adolescent sexual and
reproductive health, a clear description of adolescent sexual well-being does not yet exist. …