Proofreading by replicative DNA polymerases is a fundamental mechanism ensuring DNA
replication fidelity. In proofreading, mis-incorporated nucleotides are excised through the 3′-…

Nucleosome-nucleosome interactions drive the folding of nucleosomal arrays into dense
chromatin fibers. A better physical account of the folding of chromatin fibers is necessary to …

DNA replication introduces thousands of RNA primers into the lagging strand that need to
be removed for replication to be completed. In Escherichia coli when the replicative DNA …

Exonucleases are essential enzymes that remove nucleotides from free DNA ends during
DNA replication, DNA repair, and telomere maintenance. Due to their essential role, they are …

E lungo il libro–che è difficile da leggere, difficile nel senso di faticoso, perché a volte viene
proprio il bisogno di aprire la finestra anche se fa freddo e respirare aria pulita–ci dice come …

To measure the sequential action between different proteins that are part of a molecular
process, we need to follow their individual behavior in real time. However, standard biochemical …

In eukaryotes, DNA is compacted into chromatin and the mechanical and structural properties
of chromatin fibers play an important role in gene regulation. For well-defined, in vitro …

DNA replication introduces thousands of RNA primers into the lagging strand that need to
be removed for replication to be completed. In Escherichia coliwhen the replicative DNA …

The environmental stresses of Hong Kong:• Frequent typhoons and rainstorms;• Serious
urban heat island effect;• High population density;• Limited open space.

… 6These authors contributed equally: Thomas Dodd, Margherita Botto. ✉email: mhlamers@lumc.nl;
iivanov@gsu.edu … The two exonuclease mutants ε18 and ε65 where purified from …