There is a challenge for metalloenzymes to acquire their correct metals because some inorganic
elements form more stable complexes with proteins than do others. These preferences …

[FeFe] hydrogenases are highly active enzymes for interconverting protons and electrons
with hydrogen (H 2 ). Their active site H-cluster is formed of a canonical [4Fe-4S] cluster ([4Fe-…

Ever since the discovery of hydrogenases over 90 years ago (Stephenson and Stickland,
1931), their structure and mechanism of action have been intensively investigated. Of the three …

Protein metal-occupancy (metalation) in vivo has been elusive. To address this challenge,
the available free energies of metals have recently been determined from the responses of …

[FeFe] hydrogenases are highly efficient metalloenyzmes for hydrogen conversion. Their
active site cofactor (the H-cluster) is composed of a canonical [4Fe-4S] cluster ([4Fe-4S]H) …

The reactions are reported of NbX 5 (X = Cl, Br), TiCl 4 and Ti(O i Pr) 4 with a selection of
carboxylic acids exhibiting a known biological role, in a chlorinated solvent. The reactions of …

Protein metal-occupancy (metalation) in vivo has been elusive. Here we develop a
metalation-calculator which accounts for inter-metal competition and changing metal-availabilities …

I cluster Fe-S (Iron-sulfur cluster, ISC) sono cofattori polimetallici presenti in quasi tutti gli
organismi viventi. Dati gli importanti ruoli che le proteine Fe-S svolgono all’interno dei sistemi …

The acquisition of Co II by the corrin component of vitamin B 12 follows one of two distinct
pathways, referred to as early or late Co II insertion. The late insertion pathway exploits a Co II …

Facial expression of emotions is a powerful vehicle for communicating information about
others’ emotional states and it normally induces facial mimicry in the observers. The aim of this …