User profiles for Maria Borisovska

Maria Borisovska

Senior Data Scientist
Verified email at emdserono.com
Cited by 716

v‐SNAREs control exocytosis of vesicles from priming to fusion

M Borisovska, Y Zhao, Y Tsytsyura, N Glyvuk… - The EMBO …, 2005 - embopress.org
SNARE proteins (soluble NSF‐attachment protein receptors) are thought to be central
components of the exocytotic mechanism in neurosecretory cells, but their precise function …

Dual-transmitter neurons: functional implications of co-release and co-transmission

CE Vaaga, M Borisovska, GL Westbrook - Current opinion in neurobiology, 2014 - Elsevier
… Recently, Borisovska and colleagues, using dual patch clamp/amperometric recordings from
autaptically cultured dopaminergic periglomerular neurons, reported that stimulation with a …

[HTML][HTML] v-SNARE actions during Ca2+-triggered exocytosis

J Kesavan, M Borisovska, D Bruns - Cell, 2007 - cell.com
Assembly of SNARE proteins between opposing membranes mediates fusion of synthetic
liposomes, but it is unknown whether SNAREs act during exocytosis at the moment of Ca 2+ …

[PDF][PDF] Allosteric modulation of a human odorant receptor

…, A Dumer, C DeLaura, J Kim, GM Pierce, M Borisovska… - Current Biology, 2023 - cell.com
Odor perception is first determined by how the myriad of environmental volatiles are detected
at the periphery of the olfactory system. The combinatorial activation of dedicated odorant …

Distinct modes of dopamine and GABA release in a dual transmitter neuron

M Borisovska, ASL Bensen, G Chong… - Journal of …, 2013 - Soc Neuroscience
We now know of a surprising number of cases where single neurons contain multiple
neurotransmitters. Neurons that contain a fast-acting neurotransmitter, such as glutamate or GABA, …

Sumo: in silico sequence assessment using multiple optimization parameters

…, WG Bolick, A Najafian, M Borisovska… - … Coupling: Methods and …, 2023 - Springer
To select the most promising screening hits from antibody and VHH display campaigns for
subsequent in-depth profiling and optimization, it is highly desirable to assess and select …

Membrane-proximal tryptophans of synaptobrevin II stabilize priming of secretory vesicles

M Borisovska, YN Schwarz, M Dhara… - Journal of …, 2012 - Soc Neuroscience
Trans-soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE)
complexes formed between the SNARE motifs of synaptobrevin II, SNAP-25, and syntaxin …

SUMO – In Silico Sequence Assessment Using Multiple Optimization Parameters

…, S Malhotra, WG Bolick, A Najafian, M Borisovska… - bioRxiv, 2022 - biorxiv.org
To select the most promising screening hits from antibody and VHH display campaigns for
subsequent in-depth profiling and optimization, it is highly desirable to assess and select …

Loss of olfactory cell adhesion molecule reduces the synchrony of mitral cell activity in olfactory glomeruli

M Borisovska, MJ McGinley, AS Bensen… - The Journal of …, 2011 - Wiley Online Library
Non‐technical summary In olfactory bulb glomeruli, incoming sensory input from the nose (axodendritic
synapses) is segregated from local intraglomerular interactions (dendrodendritic …

[HTML][HTML] Syntaxins on granules promote docking of granules via interactions with munc18

M Borisovska - Scientific reports, 2018 - nature.com
SNAREs and SNARE-binding accessory proteins are believed to be central molecular
components of neurotransmitter release, although the precise sequence of molecular events …