To investigate the role of neutrophils in the efficacy of photodynamic therapy (PDT) in
rhabdomyosarcoma-bearing rats, the number of these circulating phagocytes was decreased or …

Background— Sodium channel Na V 1.5 underlies cardiac excitability and conduction. The
last 3 residues of Na V 1.5 (Ser-Ile-Val) constitute a PDZ domain–binding motif that interacts …

Neutrophils play an important role in the efficacy of photodynamic therapy (PDT). These
leukocytes rapidly accumulate into the tumor lesion after PDT and most likely eradicate the …

Transient receptor potential melastatin member 4 (TRPM4) encodes a Ca 2+ -activated, non-selective
cation channel that is functionally expressed in several tissues, including the heart…

To elucidate the mechanisms of glomerulonephritis, including Goodpasture’s syndrome,
mouse models are used that use heterologous Abs against the glomerular basement …

Background: In cardiac ventricular muscle cells, the presence of voltage-gated sodium
channels Na v 1.5 at the lateral membrane depends in part on the interaction between the …

Background: Dendritic cells (DC) can exert powerful immune stimulatory as well as regulatory
functions and are therefore important tools for therapeutic strategies. Dexamethasone (Dex…

The Cre/lox system is a potent technology to control gene expression in mouse tissues.
However, cardiac-specific Cre recombinase expression alone can lead to cardiac alterations …

TRPM4 is a calcium‐activated, voltage‐modulated, nonselective ion channel widely expressed
in various cells and tissues. TRPM4 regulates the influx of sodium ions, thus playing a …

Antibodies are immensely useful tools for biochemical research and have found application
in numerous protein detection and purification methods. Moreover, monoclonal antibodies …