Although the interaction between prokaryotic and eukaryotic microorganisms is crucial for
the functioning of ecosystems, information about the processes driving microbial interactions …

Since the discovery of penicillin, antibiotics have been instrumental in treating infectious
diseases. However, emerging antibiotic multi-resistance coinciding with a nearly exhausted …

Microorganisms produce numerous secondary metabolites (SMs) with various biological
activities. Many of their encoding gene clusters are silent under standard laboratory conditions …

Heterologous expression of multi-gene biosynthetic pathways in eukaryotic hosts is limited
by highly regulated individual monocistrons. Dissimilar to prokaryotes, each eukaryotic gene …

Polymorphonuclear granulocytes (PMNs) are indispensable for controlling life-threatening
fungal infections. In addition to various effector mechanisms, PMNs also produce extracellular …

10.7554/eLife.40969.001 The eukaryotic epigenetic machinery can be modified by bacteria
to reprogram the response of eukaryotes during their interaction with microorganisms. We …

… We thank Maria Mittag and Daniel Scheer for sharing their valuable expertise in the biology
of C. reinhardtii. Volker Schroeckh is thanked for his continuous support and helpful critical …

In order for eukaryotes to efficiently detect and respond to environmental stimuli, a myriad of
protein signaling pathways are utilized. An example of highly conserved signaling pathways …

Where does one draw the line between primary and secondary metabolism? The answer
depends on the perspective. Microbial secondary metabolites (SMs) were at first believed not …

The Aspergillus Metabolome Database is a free online resource to perform metabolite
annotation in mass spectrometry studies devoted to the genus Aspergillus. The database was …