User profiles for Maria Cristina De Rosa

maria cristina de rosa

CNR Senior Researcher
Verified email at cnr.it
Cited by 1660

Two adjacent inversions maintain genomic differentiation between migratory and stationary ecotypes of Atlantic cod

…, M Baranski, T Nome, MC De Rosa… - Molecular …, 2016 - Wiley Online Library
Atlantic cod is composed of multiple migratory and stationary populations widely distributed
in the North Atlantic Ocean. The Northeast Arctic cod (NEAC) population in the Barents Sea …

[HTML][HTML] Virtual screening and molecular dynamics simulations provide insight into repurposing drugs against SARS-CoV-2 variants Spike protein/ACE2 interface

…, C Camponeschi, F Ria, G Di Sante, MC De Rosa - Scientific Reports, 2023 - nature.com
After over two years of living with Covid-19 and hundreds of million cases worldwide there is
still an unmet need to find proper treatments for the novel coronavirus, due also to the rapid …

Haemoglobin polymorphisms affect the oxygen-binding properties in Atlantic cod populations

…, OF Wetten, MC De Rosa, C Andre… - … of the Royal …, 2009 - royalsocietypublishing.org
A major challenge in evolutionary biology is to identify the genes underlying adaptation. The
oxygen-transporting haemoglobins directly link external conditions with metabolic needs …

Allosteric properties of hemoglobin and the plasma membrane of the erythrocyte: new insights in gas transport and metabolic modulation

MC De Rosa, CC Alinovi, A Galtieri, A Russo… - IUBMB …, 2008 - Wiley Online Library
Within the red blood cell the hemoglobin molecule is subjected to modulation mechanisms,
namely homo‐ and heterotropic interactions, which optimize its functional behavior to the …

[HTML][HTML] KLF7: a new candidate biomarker and therapeutic target for high-grade serous ovarian cancer

…, M Buttarelli, A Ciucci, G Arduini, MC De Rosa… - Journal of Experimental …, 2020 - Springer
Background In spite of great progress in the surgical and clinical management, until now no
significant improvement in overall survival of High-Grade Serous Ovarian Cancer (HGSOC) …

Comparison between metabolite productions in cell culture and in whole plant of Maclura pomifera

G Delle Monache, MC De Rosa, R Scurria, A Vitali… - Phytochemistry, 1995 - Elsevier
Plant tissue cultures of Maclura pomifera showed a metabolite accumulation pattern which
was both quantitatively and qualitatively different from that of the parent plant. Triterpenes and …

[HTML][HTML] Insights from molecular dynamics simulations: structural basis for the V567D mutation-induced instability of zebrafish alpha-dystroglycan and comparison with …

…, M Bozzi, B Giardina, A Brancaccio, MC De Rosa - PLoS …, 2014 - journals.plos.org
A missense amino acid mutation of valine to aspartic acid in 567 position of alpha-dystroglycan
(DG), identified in dag1-mutated zebrafish, results in a reduced transcription and a …

[PDF][PDF] A TLR/CD44 axis regulates T cell trafficking in experimental and human multiple sclerosis

…, C Moliterni, E Giorda, M Rende, MC De Rosa… - Iscience, 2022 - cell.com
In the pathogenesis of autoimmune disorders, the modulation of leukocytes′ trafficking
plays a central role, still poorly understood. Here, we focused on the effect of TLR2 ligands in …

The plasma membrane of erythrocytes plays a fundamental role in the transport of oxygen, carbon dioxide and nitric oxide and in the maintenance of the reduced state …

MC De Rosa, CC Alinovi, A Galtieri, R Scatena… - Gene, 2007 - Elsevier
Here we review new insights into the role of the erythrocyte membrane and the implications
of its architecture on the several functions accomplished by the red blood cells. The picture …

[HTML][HTML] Identification and antitumor activity of a novel inhibitor of the NIMA-related kinase NEK6

…, M Petrillo, D Pirolli, G Scambia, MC De Rosa… - Scientific reports, 2018 - nature.com
The NIMA (never in mitosis, gene A)-related kinase-6 (NEK6), which is implicated in cell
cycle control and plays significant roles in tumorigenesis, is an attractive target for the …