Natural killer cells can discriminate between normal cells and cells that do not express
adequate amounts of major histocompatibility complex (MHC) class I molecules. The discovery, …

Recently, a number of clinical trials used either mesenchymal stem cells (MSCs) or natural
killer (NK) cells in an attempt to improve the effectiveness of hematopoietic stem cell …

In recent years, mesenchymal stem cells (MSCs) have been shown to inhibit T-lymphocyte
proliferation induced by alloantigens or mitogens. However, no substantial information is …

▪ Abstract Natural killer cells are likely to play an important role in the host defenses because
they kill virally infected or tumor cells but spare normal self-cells. The molecular mechanism …

We analyzed 21 children with leukemia receiving haploidentical hematopoietic stem cell
transplantation (haplo-HSCT) from killer immunoglobulin (Ig)–like receptors (KIR) ligand-…

On the basis of recent clinical and experimental data, natural killer (NK) cells appear to play
a crucial role in eradication of acute myeloid leukemias. In the present study, by exploiting …

The different cell types of the innate immune system can interact with each other and influence
the quality and strength of an immune response. The cross talk between natural killer (NK…

… These receptors are termed killer immunoglobulin (Ig)-like receptors (KIRs); they recognize
different allelic groups of HLA-A, HLA-B or HLA-C molecules. Other NK cell receptors involved …

The ability of tumors to manage an immune‐mediated attack has been recently included in
the “next generation” of cancer hallmarks. In solid tumors, the microenvironment that is …

BACKGROUND. Despite natural killer (NK) cells being originally identified and named because
of their ability to kill tumor cells in vitro, only limited information is available on NK cells …