Inflammation is an important part of the pathophysiology of traumatic brain injury. Although
the central nervous system differs from the other organs because of the almost complete …

Within minutes of a traumatic impact, a robust inflammatory response is elicited in the
injured brain. The complexity of this post-traumatic squeal involves a cellular component, …

Despite dramatic improvements in the management of traumatic brain injury (TBI), to date
there is no effective treatment available to patients, and morbidity and mortality remain high. …

mdash;: Neuroinflammation occuring after traumatic brain injury (TBI) is a complex phenomenon
comprising distinct cellular and molecular events involving the injured as well as the …

Chemokines and their receptors have crucial roles in the trafficking of leukocytes, and are of
particular interest in the context of the unique immune responses elicited in the central …

One and a half to two million people sustain a traumatic brain injury (TBI) in the US each year,
of which approx 70,000–90,000 will suffer from long-term disability with dramatic impacts …

: Patients with severe traumatic brain injury (TBI) show a profound acute-phase response.
Because interleukin-6 (IL-6) is an important mediator of these pathophysiological changes, IL-…

Little is known about the molecular events following severe traumatic brain injury (TBI) in
humans and to date there are no efficient therapies for the treatment of patients. In this study, …

Cytokines are involved in nerve regeneration by modulating the synthesis of neurotrophic
factors. The role played by interleukin-6 (IL-6) in promoting nerve growth factor (NGF) after …

Controlling the extent of inflammatory responses following brain injury may be beneficial
since posttraumatic intracranial inflammation has been associated with adverse outcome. In …