[HTML][HTML] Extracellular DNA, cell surface proteins and c-di-GMP promote biofilm formation in Clostridioides difficile

…, J Peltier, CL Hall, MA Harrison, M Derakhshan… - Scientific reports, 2021 - nature.com
Clostridioides difficile is the leading cause of nosocomial antibiotic-associated diarrhoea
worldwide, yet there is little insight into intestinal tract colonisation and relapse. In many …

[HTML][HTML] Environmentally sensitive hotspots in the methylome of the early human embryo

…, MN Routledge, Z Herceg, C Cuenin, M Derakhshan… - Elife, 2022 - ncbi.nlm.nih.gov
In humans, DNA methylation marks inherited from gametes are largely erased following
fertilisation, prior to construction of the embryonic methylome. Exploiting a natural experiment of …

Tissue-and ethnicity-independent hypervariable DNA methylation states show evidence of establishment in the early human embryo

M Derakhshan, NJ Kessler, M Ishida… - Nucleic acids …, 2022 - academic.oup.com
We analysed DNA methylation data from 30 datasets comprising 3474 individuals, 19
tissues and 8 ethnicities at CpGs covered by the Illumina450K array. We identified 4143 …

Developing Global Leadership in Africa

E Jordans, M Derakhshan, Z Rutter… - … Across Borders in a …, 2022 - books.google.com
There is a growing interest in leadership and leadership development in Africa. This is evident
from the increase in available literature on the topic over the past decade. For example, a …

[HTML][HTML] DNA methylation at the suppressor of cytokine signaling 3 (SOCS3) gene influences height in childhood

…, S Bayyana, SR Mansuri, M Derakhshan… - Nature …, 2023 - nature.com
Human height is strongly influenced by genetics but the contribution of modifiable epigenetic
factors is under-explored, particularly in low and middle-income countries (LMIC). We …

DNA methylation at the suppressor of cytokine signaling 3 (SOCS3) gene influences height in childhood.

…, S Sajjadi, S Bayyana, SR Mansuri, M Derakhshan… - 2023 - repository.cam.ac.uk
Human height is strongly influenced by genetics but the contribution of modifiable epigenetic
factors is under-explored, particularly in low and middle-income countries (LMIC). We …

Identification and characterisation of tissue-and ethnicity-independent hypervariable DNA methylation loci in humans

M Derakhshan - 2023 - researchonline.lshtm.ac.uk
… I, Maria Derakhshan, confirm that the work presented in this thesis is my own. Where information
has been derived from other sources, I confirm that this has been indicated in the thesis. …

Developing Global Leadership in Africa: Addressing Young Leaders' Ambitions for a People-and Community-Oriented Approach

E Jordans, M Derakhshan, Z Rutter, S de Villiers… - … Success Across Borders …, 2022 - Springer
There is an increase in literature on leadership in Africa, and this growing body of work
documents the need for a leadership transformation, as well as the need to contextualise …

[HTML][HTML] Metastable epialleles in humans

M Derakhshan, NJ Kessler, G Hellenthal, MJ Silver - Trends in Genetics, 2023 - cell.com
First identified in isogenic mice, metastable epialleles (MEs) are loci where the extent of DNA
methylation (DNAm) is variable between individuals but correlates across tissues derived …

RFID data management: challenges and opportunities

R Derakhshan, ME Orlowska… - 2007 IEEE International …, 2007 - ieeexplore.ieee.org
Radio-frequency identification (RFID) technology promises to revolutionize the way we track
items in supply chain, retail store, and asset management applications. The size and …